Optimizing fibrosis detection : a comparison of electroanatomical mapping and late enhancement gadolinium magnetic resonance imaging

التفاصيل البيبلوغرافية
العنوان: Optimizing fibrosis detection : a comparison of electroanatomical mapping and late enhancement gadolinium magnetic resonance imaging
المؤلفون: Bansmann, P. Martin, Mohsen, Yazan, Horlitz, Marc, Stöckigt, Florian
المصدر: Journal of Interventional Cardiac Electrophysiology. 67(3):571-577
مصطلحات موضوعية: Atrial cardiomyopathy, Atrial fibrillation, Atrial fibrosis, Substrate, Medicin och hälsovetenskap, Klinisk medicin, Radiologi och bildbehandling, Medical and Health Sciences, Clinical Medicine, Radiology, Nuclear Medicine and Medical Imaging
الوصف: Background: Fibrotic atrial cardiomyopathy plays an important role in determining the outcome of ablation in patients with atrial fibrillation (AF). Two main methods are being used for the evaluation of fibrosis: voltage-based high-density (HD) electroanatomical mapping (EAM) and late gadolinium enhancement MRI (LGE-MRI). The comparability between both methods in detecting fibrosis has not been systematically investigated. Methods: LGE-MRIs of the left atrium (LA) were performed in 21 patients. LA-fibrosis was evaluated using a custom-designed software generating a 3D-model of the LA. HD-electroanatomical maps were recorded in each patient. After processing the maps and the MRI models by excluding the mitral valve, pulmonary veins, and the left atrial appendage, the LGE areas were measured and compared to the low voltage areas (LVA) in the HD maps using three different cutoff values of 0.5 mV, 0.7 mV, and 1.0 mV. Results: The analysis revealed significant differences between EAM and LGE-MRI in assessing LA-fibrosis at 0.5-mV (for anterior and posterior walls) and 1.0-mV cutoffs (for anterior and posterior wall and septum). However, no significant differences were found between EAM and LGE-MRI when using a 0.7-mV cutoff for all the investigated areas. Conclusions: A voltage cutoff of 0.7 mV provided the best correlation between EAM and LGE MRI for detecting left atrial fibrosis. It supports the idea that a 0.5-mV cutoff may underestimate fibrosis, as areas with local signal voltages between 0.6 and 0.8 mV could also show LGE on MRI. Further research is needed to determine the ideal voltage cutoff for detecting left atrial fibrosis.
URL الوصول: https://lup.lub.lu.se/record/0affb5b7-c73b-4287-bdee-a72bc67049f2
http://dx.doi.org/10.1007/s10840-023-01627-4
قاعدة البيانات: SwePub
الوصف
تدمد:1383875X
DOI:10.1007/s10840-023-01627-4