Executive function in HIV-affected children and adolescents: a systematic review and meta-analyses

التفاصيل البيبلوغرافية
العنوان: Executive function in HIV-affected children and adolescents: a systematic review and meta-analyses
المؤلفون: Rowe, Kirsten, Buivydaite, Ruta, Heinsohn, Torben, Rahimzadeh, Mana, Wagner, Ryan G., Scerif, Gaia, Stein, Alan
المصدر: AIDS Care. 33(7):833-857
مصطلحات موضوعية: executive function, HIV-associated neurocognitive disorder, neurodevelopment, paediatric HIV, Perinatally acquired HIV, systematic review
الوصف: This review aimed to determine: whether EF is affected in children and adolescents (2–24-years-old) with perinatal HIV infection, perinatal HIV exposure without infection, and behaviourally acquired HIV. A systematic review (PROSPERO number: CRD42017067813) was conducted using 11 electronic databases (01.01.1981–09.07.2019) and 8 conference websites. Primary quantitative studies with EF scores on cognitive tasks and/or behavioural report measures were included. Meta-analyses were performed by EF subtype and subpopulations compared. 1789 records were found. Sixty-one studies were included in the narrative synthesis; 32 (N = 7884 participants) were included in meta-analyses. There was a distinct pattern of reduced EF in those with perinatal HIV infection on antiretroviral therapy compared to controls: pooled effect sizes were largest for verbal and visuospatial working memory, with smaller effects on planning, inhibitory control and set-shifting. Data were limited for other HIV-affected subpopulations. Perinatal HIV infection is associated with reduced EF with varying effect sizes for the different EF subtypes.
وصف الملف: print
URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-182177
قاعدة البيانات: SwePub
الوصف
تدمد:09540121
13600451
DOI:10.1080/09540121.2021.1873232