Preserved repetition in thalamic afasia. A pathophysiological hypothesis

التفاصيل البيبلوغرافية
العنوان: Preserved repetition in thalamic afasia. A pathophysiological hypothesis
المؤلفون: Nitrini, Ricardo, Lucato, Leandro T., Sitta, Maria C., Oliveira, Maíra O., Andrade, Daniel Ciampi de, Silva, Valquiria A., Carneiro, Camila G., Buchpiguel, Carlos A.
المصدر: Dementia & Neuropsychologia. June 2019 13(2)
بيانات النشر: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento, 2019.
سنة النشر: 2019
مصطلحات موضوعية: aphasia, thalamic aphasia, repetition, neuroimaging, subcortical aphasia
الوصف: The ability to repeat words is almost always preserved in thalamic aphasia. The pathophysiology of both thalamic aphasia and preservation of repetition are not fully understood. In a case of severe aphasia with preserved repetition after a left thalamic hemorrhage, MRI disclosed left thalamic lesion and loss of fractional anisotropy in the left centrum semiovale. FDG-PET showed severe hypometabolism in the left cerebral hemisphere, except for superior and transverse temporal gyri, calcarine fissure and frontopolar regions. Primary sensory function may be less functionally dependent on thalamic connections than heteromodal and paralimbic areas, which have connections with several thalamic nuclei. The extensive cortical hypometabolism due to diaschisis may have been responsible for the severity of the aphasia, whereas the less severe reduction of metabolism in the superior and transverse temporal gyri, and also, albeit less evident, in Broca’s area, might explain the preservation of repetition.
نوع الوثيقة: report
وصف الملف: text/html
اللغة: English
تدمد: 1980-5764
DOI: 10.1590/1980-57642018dn13-020015
URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000200244
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edssci.S1980.57642019000200244
قاعدة البيانات: SciELO
الوصف
تدمد:19805764
DOI:10.1590/1980-57642018dn13-020015