التفاصيل البيبلوغرافية
| العنوان: |
Salivary transforming growth factor alpha in patients with Sjögren's syndrome and reflux laryngitis |
| المؤلفون: |
Corvo, Marco Antonio dos Anjos, Eckley, Claudia Alessandra, Rizzo, Luis Vicente, Sardinha, Luiz Roberto, Rodriguez, Tomas Navarro, Bussoloti Filho, Ivo |
| المصدر: |
Brazilian Journal of Otorhinolaryngology. December 2014 80(6) |
| بيانات النشر: |
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial., 2014. |
| سنة النشر: |
2014 |
| مصطلحات موضوعية: |
Xerostomia, Laryngopharyngeal reflux, Sjögren's syndrome, Saliva, Epidermal growth factor, Transforming growth factor alpha |
| الوصف: |
Introduction: Saliva plays a key role in the homeostasis of the digestive tract, through its inorganic components and its protein growth factors. Sjögren's syndrome patients have a higher prevalence of gastroesophageal reflux disease and laryngopharyngeal reflux. Decreased salivary transforming growth factor alpha levels were observed in dyspeptic patients, but there have been no studies in patients with Sjögren's syndrome and laryngopharyngeal reflux. Objective: To compare the salivary transforming growth factor alpha levels of patients with Sjögren's syndrome and laryngopharyngeal reflux to those of healthy controls. Methods: This is a prospective controlled study. Twelve patients with Sjögren's syndrome and laryngopharyngeal reflux and 11 controls were prospectively evaluated. Spontaneous and stimulated saliva samples were obtained to establish salivary transforming growth factor alpha concentrations. Results: The salivary transforming growth factor alpha levels of patients were significantly higher than those of healthy controls. Five patients with laryngopharyngeal reflux also had erosive esophagitis; their salivary transforming growth factor alpha levels were comparable to controls. Conclusion: Salivary transforming growth factor alpha level was significantly higher in patients with Sjögren's syndrome and laryngopharyngeal reflux when compared to the control group. |
| نوع الوثيقة: |
article |
| وصف الملف: |
text/html |
| اللغة: |
English |
| تدمد: |
1808-8694 |
| DOI: |
10.1016/j.bjorl.2014.08.006 |
| URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000600462 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edssci.S1808.86942014000600462 |
| قاعدة البيانات: |
SciELO |
Full Text Finder