Academic Journal

The serum matrix metalloproteinase-9 level is an independent predictor of recurrence after ablation of persistent atrial fibrillation

التفاصيل البيبلوغرافية
العنوان: The serum matrix metalloproteinase-9 level is an independent predictor of recurrence after ablation of persistent atrial fibrillation
المؤلفون: Wu, Gang, Wang, Shun, Cheng, Mian, Peng, Bin, Liang, Jingjun, Huang, He, Jiang, Xuejun, Zhang, Lizhi, Yang, Bo, Cha, Yongmei, Jiang, Hong, Huang, Congxin
المصدر: Clinics. May 2016 71(5)
بيانات النشر: Faculdade de Medicina / USP, 2016.
سنة النشر: 2016
مصطلحات موضوعية: Matrix Metalloproteinase-9, Atrial Fibrillation, Recurrence, Catheter Ablation
الوصف: OBJECTIVES: This study investigated whether the serum matrix metalloproteinase-9 level is an independent predictor of recurrence after catheter ablation for persistent atrial fibrillation. METHODS: Fifty-eight consecutive patients with persistent atrial fibrillation were enrolled and underwent catheter ablation. The serum matrix metalloproteinase-9 level was detected before ablation and its relationship with recurrent arrhythmia was analyzed at the end of the follow-up. RESULTS: After a mean follow-up of 12.1±7.2 months, 21 (36.2%) patients had a recurrence of their arrhythmia after catheter ablation. At baseline, the matrix metalloproteinase-9 level was higher in the patients with recurrence than in the non-recurrent group (305.77±88.90 vs 234.41±93.36 ng/ml, respectively, p=0.006). A multivariate analysis showed that the matrix metalloproteinase-9 level was an independent predictor of arrhythmia recurrence, as was a history of atrial fibrillation and the diameter of the left atrium. CONCLUSION: The serum matrix metalloproteinase-9 level is an independent predictor of recurrent arrhythmia after catheter ablation in patients with persistent atrial fibrillation.
نوع الوثيقة: article
وصف الملف: text/html
اللغة: English
تدمد: 1807-5932
DOI: 10.6061/clinics/2016(05)02
URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322016000500251
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edssci.S1807.59322016000500251
قاعدة البيانات: SciELO
الوصف
تدمد:18075932
DOI:10.6061/clinics/2016(05)02