Academic Journal

Surgical antibiotic prophylaxis: is the clinical practice based on evidence?

التفاصيل البيبلوغرافية
العنوان: Surgical antibiotic prophylaxis: is the clinical practice based on evidence?
المؤلفون: Pereira, Lucas Borges, Feliciano, Cinara Silva, Siqueira, Diego Silva, Bellissimo-Rodrigues, Fernando, Pereira, Leonardo Régis Leira
المصدر: einstein (São Paulo). January 2020 18
بيانات النشر: Instituto Israelita de Ensino e Pesquisa Albert Einstein, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Drug utilization review, Antibiotic prophylaxis, Drug resistance, microbial, Surgical wound infection/prevention & control, Infection control
الوصف: Objective: To assess the surgical antibiotic prophylaxis. Methods: This was a descriptive study performed at a public tertiary care university hospital gathering prescription, sociodemographic and hospitalization data of inpatients admitted in 2014 who used antimicrobial drugs. This data were obtained from the hospital electronic database. The antimicrobial data were classified according to the anatomical, therapeutic chemical/defined daily dose per 1,000 inpatients. An exploratory analysis was performed using principal component analysis. Results: A total of 5,182 inpatients were prescribed surgical antibiotic prophylaxis. Of the total antimicrobial use, 11.7% were for surgical antibiotic prophylaxis. The orthopedic, thoracic and cardiovascular postoperative units, and postoperative intensive care unit comprised more than half of the total surgical antibiotic prophylaxis use (56.3%). The duration of antimicrobial use of these units were 2.2, 2.0, and 1.4 days, respectively. Third-generation cephalosporins and fluoroquinolones had the longest use among antimicrobial classes. Conclusion: Surgical antibiotic prophylaxis was inadequate in the orthopedic, postoperative intensive care, thoracic and cardiovascular postoperative, gynecology and obstetrics, and otolaryngology units. Therefore, the development and implementation of additional strategies to promote surgical antibiotic stewardship at hospitals are essential.
نوع الوثيقة: article
وصف الملف: text/html
اللغة: English
تدمد: 1679-4508
DOI: 10.31744/einstein_journal/2020ao5427
URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082020000100281
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edssci.S1679.45082020000100281
قاعدة البيانات: SciELO
الوصف
تدمد:16794508
DOI:10.31744/einstein_journal/2020ao5427