التفاصيل البيبلوغرافية
العنوان: |
Calcineurin inhibitors revisited: A new paradigm for COVID-19? |
المؤلفون: |
Hage, René, Steinack, Carolin, Schuurmans, Macé M. |
المصدر: |
Brazilian Journal of Infectious Diseases. August 2020 24(4) |
بيانات النشر: |
Brazilian Society of Infectious Diseases, 2020. |
سنة النشر: |
2020 |
مصطلحات موضوعية: |
Cytokine storm, Hyperinflammation, Transplantation, ARDS |
الوصف: |
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can cause mild, moderate or severe disease (COVID-19). In severe disease, there is hyperinflammation causing severe symptoms. Severe COVID-19 is an immunological phenomenon, rather than a direct viral damage disease. Therapies for COVID-19 are all investigational therapies. In case of severe disease, treatment with a calcineurin inhibitor could be promising. In this article we explain the mechanisms of calcineurin inhibitor treatment for COVID-19, based on experiences seen in solid organ transplant recipients who suffered from COVID-19. |
نوع الوثيقة: |
article |
وصف الملف: |
text/html |
اللغة: |
English |
تدمد: |
1413-8670 |
DOI: |
10.1016/j.bjid.2020.06.005 |
URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702020000400365 |
Rights: |
info:eu-repo/semantics/openAccess |
رقم الانضمام: |
edssci.S1413.86702020000400365 |
قاعدة البيانات: |
SciELO |