التفاصيل البيبلوغرافية
| العنوان: |
Molecular investigation of a fungemia outbreak due to Candida parapsilosis in an intensive care unit |
| المؤلفون: |
Dizbay, Murat, Kalkanci, Ayse, Sezer, Busra Ergut, Aktas, Firdevs, Aydogan, Sibel, Fidan, Isil, Kustimur, Semra, Sugita, Takashi |
| المصدر: |
Brazilian Journal of Infectious Diseases. October 2008 12(5) |
| بيانات النشر: |
Brazilian Society of Infectious Diseases, 2008. |
| سنة النشر: |
2008 |
| مصطلحات موضوعية: |
Candidemia, Candida parapsilosis, nosocomial outbreak, intensive care unit, RAPD, DNA sequencing |
| الوصف: |
We investigated a nosocomial cluster of four Candida parapsilosis fungemia episodes that occurred in a neurological intensive care unit over a two-week period. The four infected patients had received parenteral nutrition through central lines, and all four had catheter-related candidemia. All of the isolates were susceptible to all of the antifungals tested, including amphotericin B, fluconazole, voriconazole, and caspofungin. They had strictly related fingerprints, based on randomly amplified polymorphic DNA analysis. Additional DNA sequencing data revealed that they were same strain. Although no isolate of Candida parapsilosis was recovered from other clinical, surveillance, or environmental samples, nosocomial spread of this yeast ceased, following the reinforcement of infection-control measures. Candida parapsilosis may require an intravascular foreign body to cause fungemia, but this outbreak shows that it can be transmitted nosocomially and can cause epidemics. |
| نوع الوثيقة: |
article |
| وصف الملف: |
text/html |
| اللغة: |
English |
| تدمد: |
1413-8670 |
| DOI: |
10.1590/S1413-86702008000500010 |
| URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500010 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edssci.S1413.86702008000500010 |
| قاعدة البيانات: |
SciELO |
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