التفاصيل البيبلوغرافية
| العنوان: |
New Approach for the Stereoselective Synthesis of (+)-epi-Cytoxazone |
| المؤلفون: |
Miranda, Izabel L., Sartori, Suélen K., Diaz, Marisa A. N., Diaz-Muñoz, Gaspar |
| المصدر: |
Journal of the Brazilian Chemical Society. March 2019 30(3) |
| بيانات النشر: |
Sociedade Brasileira de Química, 2019. |
| سنة النشر: |
2019 |
| مصطلحات موضوعية: |
cytoxazone, epi-cytoxazone, 2,3-O-(3-pentylidene)-(R)-glyceraldehyde, Wittig olefination, stereoselective dihydroxylation |
| الوصف: |
The stereoselective total synthesis of (+)-epi-cytoxazone was performed satisfactorily in 8 steps, in 17% overall yield, via a novel route from 2,3-O-(3-pentylidene)-(R)-glyceraldehyde. The bulky group alkene-ketal allowed intramolecular control of the target molecule's asymmetric centers in the dihydroxylation step by promoting the approach of OsO4 to the face opposite to that of the ketal group. |
| نوع الوثيقة: |
article |
| وصف الملف: |
text/html |
| اللغة: |
English |
| تدمد: |
0103-5053 |
| DOI: |
10.21577/0103-5053.20180212 |
| URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019000300585 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edssci.S0103.50532019000300585 |
| قاعدة البيانات: |
SciELO |
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