التفاصيل البيبلوغرافية
| العنوان: |
Synthesis of platinum complexes from N-benzyl ethylenediamine derivatives |
| المؤلفون: |
Almeida, Mauro V. de, Cesar, Eloi T., Felício, Emanoel de C. A., Fontes, Ana Paula S., Robert-Gero, Malka |
| المصدر: |
Journal of the Brazilian Chemical Society. April 2000 11(2) |
| بيانات النشر: |
Sociedade Brasileira de Química, 2000. |
| سنة النشر: |
2000 |
| مصطلحات موضوعية: |
platinum(II) complexes, N-benzylethylenediamine, anticancer agents, substitution reactions |
| الوصف: |
N-benzylethylenediamine derivatives have been prepared in good yields using methodology diferent than that described in the literature. ¹H and 13C NMR spectra were used to characterize those compounds. Nine new platinum(II) complexes, analogs of cisplatin and carboplatin, containing these ligands have been prepared and characterized. Preliminary in vitro tests against buccal human carcinoma cell lines (KB cells) showed that the complexes are cytotoxic. |
| نوع الوثيقة: |
article |
| وصف الملف: |
text/html |
| اللغة: |
English |
| تدمد: |
0103-5053 |
| DOI: |
10.1590/S0103-50532000000200009 |
| URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200009 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edssci.S0103.50532000000200009 |
| قاعدة البيانات: |
SciELO |
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