Academic Journal

Evaluation of the use of tranexamic acid in total knee arthroplasty

التفاصيل البيبلوغرافية
العنوان: Evaluation of the use of tranexamic acid in total knee arthroplasty
المؤلفون: Almeida, Mariana Diana Chaves de, Albuquerque, Rodrigo Pires e, Palhares, Guilherme Mathias, Almeida, Juliana Patrícia Chaves de, Barretto, João Mauricio, Cavanellas, Naasson
المصدر: Revista Brasileira de Ortopedia. December 2018 53(6)
بيانات النشر: Sociedade Brasileira de Ortopedia e Traumatologia, 2018.
سنة النشر: 2018
مصطلحات موضوعية: Tranexamic acid, Bleeding, Orthopedic, Total knee arthroplasty, Blood transfusion, Blood volume
الوصف: Objective: Evaluate the efficacy of tranexamic acid in reducing bleeding in patients undergoing total knee arthroplasty. Methods: 101 patients were randomized into two groups: the tranexamic acid group (n = 51) and the placebo group (n = 50). Patients were compared regarding the following parameters: reduction of hemoglobin, total estimated blood loss, drain output, and postoperative blood transfusion rate. Results: Comparing the groups, there were statistically significant differences (p < 0.05) in the following parameters: reduction of hemoglobin, decreased hematocrit, estimated blood loss, and drain output. All values were lower in the tranexamic acid group. Only placebo group patients required blood transfusion. Conclusion: The use of intravenous tranexamic acid is effective to reduce bleeding in patients undergoing total knee arthroplasty.
نوع الوثيقة: article
وصف الملف: text/html
اللغة: English
تدمد: 0102-3616
DOI: 10.1016/j.rboe.2018.09.008
URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162018000600761
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edssci.S0102.36162018000600761
قاعدة البيانات: SciELO
الوصف
تدمد:01023616
DOI:10.1016/j.rboe.2018.09.008