التفاصيل البيبلوغرافية
العنوان: |
Evaluation of the use of tranexamic acid in total knee arthroplasty |
المؤلفون: |
Almeida, Mariana Diana Chaves de, Albuquerque, Rodrigo Pires e, Palhares, Guilherme Mathias, Almeida, Juliana Patrícia Chaves de, Barretto, João Mauricio, Cavanellas, Naasson |
المصدر: |
Revista Brasileira de Ortopedia. December 2018 53(6) |
بيانات النشر: |
Sociedade Brasileira de Ortopedia e Traumatologia, 2018. |
سنة النشر: |
2018 |
مصطلحات موضوعية: |
Tranexamic acid, Bleeding, Orthopedic, Total knee arthroplasty, Blood transfusion, Blood volume |
الوصف: |
Objective: Evaluate the efficacy of tranexamic acid in reducing bleeding in patients undergoing total knee arthroplasty. Methods: 101 patients were randomized into two groups: the tranexamic acid group (n = 51) and the placebo group (n = 50). Patients were compared regarding the following parameters: reduction of hemoglobin, total estimated blood loss, drain output, and postoperative blood transfusion rate. Results: Comparing the groups, there were statistically significant differences (p < 0.05) in the following parameters: reduction of hemoglobin, decreased hematocrit, estimated blood loss, and drain output. All values were lower in the tranexamic acid group. Only placebo group patients required blood transfusion. Conclusion: The use of intravenous tranexamic acid is effective to reduce bleeding in patients undergoing total knee arthroplasty. |
نوع الوثيقة: |
article |
وصف الملف: |
text/html |
اللغة: |
English |
تدمد: |
0102-3616 |
DOI: |
10.1016/j.rboe.2018.09.008 |
URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162018000600761 |
Rights: |
info:eu-repo/semantics/openAccess |
رقم الانضمام: |
edssci.S0102.36162018000600761 |
قاعدة البيانات: |
SciELO |