التفاصيل البيبلوغرافية
| العنوان: |
Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni |
| المؤلفون: |
Hamed, Manal A, Hetta, Mona H |
| المصدر: |
Memórias do Instituto Oswaldo Cruz. November 2005 100(7) |
| بيانات النشر: |
Instituto Oswaldo Cruz, Ministério da Saúde, 2005. |
| سنة النشر: |
2005 |
| مصطلحات موضوعية: |
Citrus reticulata, Mirazid, schistosomiasis, enzymes/worm burden, ova count |
| الوصف: |
This work has been carried out to investigate the effect of Schistosoma mansoni infection on mice livers after treatment with the ethanolic extract of Citrus reticulata root or the oleo-resin extract from Myrrh of Commiphora molmol tree (Mirazid), as a new antishistosomal drug. Marker enzymes for different cell organelles were measured; succinate dehydrogenase (SDH); lactate dehydrogenase (LDH) and its isoenzymes; glucose-6-phosphatase (G-6-Pase); acid phosphatase (AP) and 5'- nucleotidase. Liver function enzymes; aspartate aminotransferase (AST); alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were also estimated. Parasitological studies through ova count and worm burden will also be taken into consideration. The results showed a marked reduction in SDH, LDH, AST, and ALT enzyme activities and a significant increase in G-6-Pase, AP, 5'- nucleotidase, and ALP after S. mansoni infection. A noticeable alteration in LDH subunits were also noticed. Treatment with C. reticulata or Mirazid improved all the previous enzyme activities with a noticeable reduction in ova count and worm burden. |
| نوع الوثيقة: |
article |
| وصف الملف: |
text/html |
| اللغة: |
English |
| تدمد: |
0074-0276 |
| DOI: |
10.1590/S0074-02762005000700017 |
| URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000700017 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edssci.S0074.02762005000700017 |
| قاعدة البيانات: |
SciELO |