Academic Journal

Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies

التفاصيل البيبلوغرافية
العنوان: Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
المؤلفون: Ré, Viviana, Gallego, Sandra, Treviño, Elena, Barbás, Gabriela, Domínguez, Claudia, Elbarcha, Osvaldo, Bepre, Héctor, Contigiani, Marta
المصدر: Memórias do Instituto Oswaldo Cruz. May 2005 100(3)
بيانات النشر: Instituto Oswaldo Cruz, Ministério da Saúde, 2005.
سنة النشر: 2005
مصطلحات موضوعية: hepatitis C virus (HCV), HCV screening test, sensitivity
الوصف: This study was conducted to compare among the most recent generation of five screening tests licensed in Argentina, in order to evaluate which of the tests has the best sensitivity for detection of antibodies against hepatitis C virus (HCV). The tests analyzed were: Detect-HCV™ (3.0) Biochem ImmunoSystems, Canada; Hepatitis C EIA Wiener Lab., Argentina; Equipar HCV Ab, Italy; Murex HCV 4.0, UK and Serodia-HCV particles agglutination test, Japan. The results obtained showed high discrepancy between the different kits used and show that some of the tests assessed have a low sensitivity for anti-HCV detection in both chronic infections and early seroconversion, and indicate that among the commercially available kits in Argentina, Murex HCV 4.0 (UK) and Serodia-HCV particles agglutination test (Japan) have the best sensitivity for HCV screening. Although the sensitivity of the assays is the first parameter to be considered for blood screening, more studies should be carried out to assess the specificity of such assays.
نوع الوثيقة: article
وصف الملف: text/html
اللغة: English
تدمد: 0074-0276
DOI: 10.1590/S0074-02762005000300016
URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000300016
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edssci.S0074.02762005000300016
قاعدة البيانات: SciELO
الوصف
تدمد:00740276
DOI:10.1590/S0074-02762005000300016