التفاصيل البيبلوغرافية
| العنوان: |
Comparison of propofol and midazolam on patients undergoing spinal surgery with intraoperative wake-up test: randomized clinical trial |
| المؤلفون: |
Canbay, Ozgur, Altiparmak, Basak, Celebi, Nalan, Karagoz, Heves, Saricaoglu, Fatma |
| المصدر: |
Revista Brasileira de Anestesiologia. December 2015 65(6) |
| بيانات النشر: |
Sociedade Brasileira de Anestesiologia, 2015. |
| سنة النشر: |
2015 |
| مصطلحات موضوعية: |
Wake-up test, Propofol, Midazolam, BIS, Spine surgery |
| الوصف: |
BACKGROUND AND OBJECTIVES: Instrumentation in correction operations for spinal deformities carries a 0.5-5% risk of injuring the spinal cord. The wake-up test is used for early detection of these injuries. In this study we compared the effects of propofol and midazolam during wake-up test in scoliosis surgery. METHODS: Thirty patients were randomly assigned as group P and group M. Anesthesia was induced with propofol 2.5 mg kg-1 for group P or midazolam 0.5 mg kg-1 for group M with remifentanil 0.5 µg kg-1 and cisatracurium 0.15 mg kg-1 for both groups. At the maintenance of anesthesia O2/air and infusions of remifentanil and cisatracurium were used. In group P, propofol 6-10 mg kg-1 h-1 and in group M, midazolam 0.5 mg mg kg-1 were preferred. Approximately 15 min before the wake-up test, all drugs were discontinued. At the wake-up test, anesthesiologist asked the patients to open their eyes and squeeze his/her hand at every 30 s until the patients responded. Then patients were told to wiggle their toes. Hemodynamic parameters, time of eye-opening, appropriate movement upon verbal command were evaluated. BIS frequency throughout the operation was recorded. RESULTS: The eye opening time was 9 ± 2.15 min in group P and 7 ± 3.15 min in group M. Motor movement time was 12 ± 2.55 min in group P and 21.25 ± 3.93 min in group M. CONCLUSION: Propofol provided better wake-up conditions and conducted a better neurologic assessment within the same BIS values than midazolam. |
| نوع الوثيقة: |
article |
| وصف الملف: |
text/html |
| اللغة: |
English |
| تدمد: |
0034-7094 |
| DOI: |
10.1016/j.bjane.2013.10.003 |
| URL الوصول: |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942015000600470 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edssci.S0034.70942015000600470 |
| قاعدة البيانات: |
SciELO |
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