Patent
Vaccine against salmonid rickettsial septicaemia based on Arthrobacter cells
| العنوان: | Vaccine against salmonid rickettsial septicaemia based on Arthrobacter cells |
|---|---|
| Patent Number: | 7,707,970 |
| تاريخ النشر: | May 04, 2010 |
| Appl. No: | 11/937642 |
| Application Filed: | November 09, 2007 |
| مستخلص: | A vaccine based on live Arthrobacter cells is useful in preventing piscirickettsiosis in fish. |
| Inventors: | Salonius, Kira (Victoria, CA); Griffiths, Steven Gareth (Moncton, CA) |
| Assignees: | Novartis AG (Basel, CH) |
| Claim: | 1. A method of treating or preventing a disease in a fish, the method comprising: administering to the fish an immunogenic composition comprising an Arthrobacter , wherein the disease is caused by Piscirickettsia salmonis. |
| Claim: | 2. The method of claim 1 , wherein the disease is piscirickettsiosis. |
| Claim: | 3. The method of claim 1 , wherein the fish is a salmonid fish. |
| Claim: | 4. The method of claim 1 , wherein the fish is Salmo salar. |
| Claim: | 5. The method of claim 1 , wherein the fish is an Ocnorhyncus species. |
| Claim: | 6. The method of claim 1 , wherein the fish is selected from the group consisting of: Oncorhyncus kisutch, Oncorhyncus tshawytscha, Oncorhyncus masou, Oncorhyncus gorbuscha , and Oncorhyncus mykiss. |
| Claim: | 7. The method of claim 1 , wherein the fish is an Oncorhyncus kisutch. |
| Claim: | 8. The method of claim 1 , wherein the Arthrobacter is live. |
| Claim: | 9. The method of claim 8 , wherein the composition further comprises a killed Arthrobacter. |
| Claim: | 10. The method of claim 1 , wherein the Arthrobacter is killed. |
| Claim: | 11. The method of claim 1 , wherein the Arthrobacter is an Arthrobacter species deposited under ATCC accession no. 55921. |
| Claim: | 12. The method of claim 1 , wherein the Arthrobacter is a species having a 16S rDNA sequence that is identical to or less than 3% divergent to the 16S rDNA sequence of an Arthrobacter species deposited under ATCC accession no. 55921. |
| Claim: | 13. The method of claim 1 , wherein the composition further comprises at least one immunogen other than the Arthrobacter. |
| Claim: | 14. The method of claim 13 , wherein the at least one immunogen is a Piscirickettsia salmonis antigen. |
| Claim: | 15. The method of claim 14 , wherein the Piscirickettsia salmonis antigen is a nucleic acid expression vector capable of expressing the Piscirickettsia salmonis antigen. |
| Claim: | 16. The method of claim 13 , wherein the at least one immunogen is a Piscirickettsia salmonis. |
| Claim: | 17. The method of claim 16 , wherein the Piscirickettsia salmonis is inactivated. |
| Claim: | 18. The method of claim 16 , wherein the Piscirickettsia salmonis is killed. |
| Claim: | 19. The method of claim 1 , wherein the administering is by intraperitoneal injection of the fish. |
| Claim: | 20. The method of claim 1 , wherein the administering is by immersion of the fish. |
| Current U.S. Class: | 119/215 |
| Patent References Cited: | 6627203 September 2003 Griffiths et al. 6913754 July 2005 Griffiths et al. 2003/0165526 September 2003 Kuzyk et al. 2005/0202039 September 2005 Griffiths et al. 2006/0127416 June 2006 Griffiths et al. 2009/0162391 June 2009 Kirke et al. |
| Primary Examiner: | Abbott, Yvonne R. |
| رقم الانضمام: | edspgr.07707970 |
| قاعدة البيانات: | USPTO Patent Grants |
| الوصف غير متاح. |