Patent
Calcitonin analogs
| العنوان: | Calcitonin analogs |
|---|---|
| Patent Number: | 4,604,236 |
| تاريخ النشر: | August 05, 1986 |
| Appl. No: | 06/713,156 |
| Application Filed: | March 18, 1985 |
| مستخلص: | New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a serine in position 13. The position 13 serine is omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides. |
| Inventors: | Orlowski, Ronald C. (Frankfort, IL); Seyler, Jay K. (Bourbonnais, IL) |
| Claim: | 1. The peptide having the structure: ##STR28## |
| Claim: | 2. The peptide having the structure: ##STR29## |
| Claim: | 3. The peptide having the structure: ##STR30## |
| Claim: | 4. The peptide having the structure: ##STR31## where R.sub.1 is S-n-alkyl, Cys or H and R.sub.2 is S-n-alkyl or H, R.sub.1 being S-n-alkyl, Cys or H when R.sub.2 is H and R.sub.2 being S-n-alkyl or H when R.sub.1 is H. |
| Claim: | 5. The peptide having the structure: ##STR32## |
| Claim: | 6. The peptide having the structure: ##STR33## |
| Current U.S. Class: | 530/307 |
| Current International Class: | C07K 736 |
| Patent References Cited: | 4086221 April 1978 Sakakihara et al. |
| Other References: | Gaddum, J. Pharm. Pharmacol., 6, 345-358, (1953). |
| Primary Examiner: | Moyer, Donald B. |
| Assistant Examiner: | Moezie, F. T. |
| رقم الانضمام: | edspgr.04604236 |
| قاعدة البيانات: | USPTO Patent Grants |
| ResultId |
1 |
|---|---|
| Header |
edspgr USPTO Patent Grants edspgr.04604236 646 3 Patent patent 645.93701171875 |
| PLink |
https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edspgr&AN=edspgr.04604236&custid=s6537998&authtype=sso |
| FullText |
Array
(
[Availability] => 0
)
Array ( [0] => Array ( [Url] => https://ppubs.uspto.gov/pubwebapp/external.html?q=(%224%2C604%2C236%22).pn.&db=USPAT&type=ids [Name] => EDS - USPTO Patent Grants [Category] => fullText [Text] => View record in USPTO Patent Grants [MouseOverText] => View record in USPTO Patent Grants ) ) |
| Items |
Array
(
[Name] => Title
[Label] => Title
[Group] => Ti
[Data] => Calcitonin analogs
)
Array ( [Name] => DocumentID [Label] => Patent Number [Group] => Patent [Data] => 4,604,236 ) Array ( [Name] => DateEntry [Label] => Publication Date [Group] => Patent [Data] => August 05, 1986 ) Array ( [Name] => DocumentID [Label] => Appl. No [Group] => Patent [Data] => 06/713,156 ) Array ( [Name] => DateFiled [Label] => Application Filed [Group] => Patent [Data] => March 18, 1985 ) Array ( [Name] => Abstract [Label] => Abstract [Group] => Ab [Data] => New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a serine in position 13. The position 13 serine is omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides. ) Array ( [Name] => Author [Label] => Inventors [Group] => Patent [Data] => <searchLink fieldCode="ZA" term="%22Orlowski%2C+Ronald+C%2E%22">Orlowski, Ronald C.</searchLink> (Frankfort, IL); <searchLink fieldCode="ZA" term="%22Seyler%2C+Jay+K%2E%22">Seyler, Jay K.</searchLink> (Bourbonnais, IL) ) Array ( [Name] => Comment [Label] => Claim [Group] => Patent [Data] => 1. The peptide having the structure: ##STR28## ) Array ( [Name] => Comment [Label] => Claim [Group] => Patent [Data] => 2. The peptide having the structure: ##STR29## ) Array ( [Name] => Comment [Label] => Claim [Group] => Patent [Data] => 3. The peptide having the structure: ##STR30## ) Array ( [Name] => Comment [Label] => Claim [Group] => Patent [Data] => 4. The peptide having the structure: ##STR31## where R.sub.1 is S-n-alkyl, Cys or H and R.sub.2 is S-n-alkyl or H, R.sub.1 being S-n-alkyl, Cys or H when R.sub.2 is H and R.sub.2 being S-n-alkyl or H when R.sub.1 is H. ) Array ( [Name] => Comment [Label] => Claim [Group] => Patent [Data] => 5. The peptide having the structure: ##STR32## ) Array ( [Name] => Comment [Label] => Claim [Group] => Patent [Data] => 6. The peptide having the structure: ##STR33## ) Array ( [Name] => CodeClass [Label] => Current U.S. Class [Group] => Patent [Data] => 530/307 ) Array ( [Name] => CodeClass [Label] => Current International Class [Group] => Patent [Data] => C07K 736 ) Array ( [Name] => Ref [Label] => Patent References Cited [Group] => Patent [Data] => <searchLink fieldCode="RF" term="%224086221%22">4086221</searchLink> April 1978 Sakakihara et al. ) Array ( [Name] => Ref [Label] => Other References [Group] => Patent [Data] => Gaddum, J. Pharm. Pharmacol., 6, 345-358, (1953). ) Array ( [Name] => AuthorEditor [Label] => Primary Examiner [Group] => Patent [Data] => <searchLink fieldCode="ZE" term="%22Moyer%2C+Donald+B%2E%22">Moyer, Donald B.</searchLink> ) Array ( [Name] => AuthorEditor [Label] => Assistant Examiner [Group] => Patent [Data] => <searchLink fieldCode="ZE" term="%22Moezie%2C+F%2E+T%2E%22">Moezie, F. T.</searchLink> ) Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edspgr.04604236 ) |
| RecordInfo |
Array
(
[BibEntity] => Array
(
[Languages] => Array
(
[0] => Array
(
[Text] => English
)
)
[Titles] => Array
(
[0] => Array
(
[TitleFull] => Calcitonin analogs
[Type] => main
)
)
)
[BibRelationships] => Array
(
[HasContributorRelationships] => Array
(
[0] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Orlowski, Ronald C.
)
)
)
[1] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Seyler, Jay K.
)
)
)
)
[IsPartOfRelationships] => Array
(
[0] => Array
(
[BibEntity] => Array
(
[Dates] => Array
(
[0] => Array
(
[D] => 05
[M] => 08
[Text] => August 05, 1986
[Type] => published
[Y] => 1986
)
)
)
)
)
)
)
|
| IllustrationInfo |