التفاصيل البيبلوغرافية
| العنوان: |
Calcitonin analogs |
| Patent Number: |
4,604,236 |
| تاريخ النشر: |
August 05, 1986 |
| Appl. No: |
06/713,156 |
| Application Filed: |
March 18, 1985 |
| مستخلص: |
New peptides are disclosed which have biological activity of the same type as known calcitonins and which do not have a serine in position 13. The position 13 serine is omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides. |
| Inventors: |
Orlowski, Ronald C. (Frankfort, IL); Seyler, Jay K. (Bourbonnais, IL) |
| Claim: |
1. The peptide having the structure: ##STR28## |
| Claim: |
2. The peptide having the structure: ##STR29## |
| Claim: |
3. The peptide having the structure: ##STR30## |
| Claim: |
4. The peptide having the structure: ##STR31## where R.sub.1 is S-n-alkyl, Cys or H and R.sub.2 is S-n-alkyl or H, R.sub.1 being S-n-alkyl, Cys or H when R.sub.2 is H and R.sub.2 being S-n-alkyl or H when R.sub.1 is H. |
| Claim: |
5. The peptide having the structure: ##STR32## |
| Claim: |
6. The peptide having the structure: ##STR33## |
| Current U.S. Class: |
530/307 |
| Current International Class: |
C07K 736 |
| Patent References Cited: |
4086221 April 1978 Sakakihara et al. |
| Other References: |
Gaddum, J. Pharm. Pharmacol., 6, 345-358, (1953). |
| Primary Examiner: |
Moyer, Donald B. |
| Assistant Examiner: |
Moezie, F. T. |
| رقم الانضمام: |
edspgr.04604236 |
| قاعدة البيانات: |
USPTO Patent Grants |