التفاصيل البيبلوغرافية
| العنوان: |
MIXING BAG WITH INTEGRAL SPARGER AND SENSOR RECEIVER |
| Document Number: |
20120152769 |
| تاريخ النشر: |
June 21, 2012 |
| Appl. No: |
13/405609 |
| Application Filed: |
February 27, 2012 |
| مستخلص: |
A mixing bag for use in bioprocessing in which a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device is disclosed. The bag may include an integral sparger and sensor receiver. Related methods are also disclosed. |
| Inventors: |
Terentiev, Alexandre N. (Lexington, KY, US); Terentyev, Sergey (Lexington, KY, US) |
| Claim: |
1. An apparatus for receiving a fluid and sensing a characteristic thereof using a sensor element for the fluid, comprising: a vessel having a flexible sidewall at least partially defining an interior compartment, a portion of the vessel formed by the flexible sidewall having no predetermined shape and capable of assuming a particular shape based on the presence of the fluid in the interior compartment; and a receiver connected to the vessel for receiving the sensor element. |
| Claim: |
2. The apparatus of claim 1, further including a tube for supporting the sensor element, the tube being adapted for positioning in the receiver. |
| Claim: |
3. The apparatus of claim 2, wherein the tube is positioned in contact with the fluid. |
| Claim: |
4. The apparatus of claim 2, wherein the tube is adapted for positioning in the receiver in contact with the fluid when present. |
| Claim: |
5. The apparatus of claim 1, wherein a fluid-impervious seal connects the receiver to the vessel. |
| Claim: |
6. The apparatus of claim 1, wherein the receiver includes a portion adapted for connecting with a tube. |
| Claim: |
7. The apparatus of claim 6, wherein the portion comprises a barb arranged on a tubular portion of the receiver. |
| Claim: |
8. The apparatus of claim 1, wherein the receiver includes a tubular portion external to the vessel. |
| Claim: |
9. The apparatus of claim 1, wherein the tubular portion includes a passage for receiving the sensor element. |
| Claim: |
10. An apparatus, comprising: a flexible vessel having an interior space bounded by a surface, the flexible vessel being selectively movable between an extended position wherein a first portion and an opposing second portion are spaced apart and a collapsed position wherein the first portion and the opposing second portion are moved closer together relative to the extended position; a connector secured to the second end of the flexible vessel, the connector having an opening extending therethrough that communicates with the space of the flexible vessel; an elongated probe having a first end and an opposing second end, the second end of the probe being positioned within the interior space of the flexible vessel, the second end of the probe being configured to pass through the opening of the connector; and a sealing layer for sealing opening of the connector. |
| Claim: |
11. The apparatus of claim 10, wherein the vessel comprises a bag. |
| Claim: |
12. The apparatus of claim 10, wherein the sealing layer comprises a flexible plastic material. |
| Claim: |
13. The apparatus of claim 10, wherein the probe carries a sensor element for contacting the fluid. |
| Claim: |
14. The apparatus of claim 10, wherein the connector is connected to the flexible vessel. |
| Claim: |
15. The apparatus of claim 10, further including an adhesive for securing the sealing layer to the connector. |
| Claim: |
16. The apparatus of claim 10, wherein the second end of the probe is positioned within the interior space. |
| Claim: |
17. The apparatus of claim 10, wherein the interior space is sealed by the probe. |
| Claim: |
18. An apparatus comprising: a flexible vessel including a passage, said vessel having an interior surface extending between a first end and an opposing second end, the flexible vessel being selectively movable between an extended position wherein the first end and the opposing second end are spaced apart and a collapsed position wherein the first end and the opposing second end are moved closer together relative to the extended position; a connector secured to the second end of the flexible vessel, the connector having an opening extending therethrough that communicates with the interior compartment of the flexible vessel, and an elongated tube having a first end and an opposing second end, the second end of the tube being positioned within the interior compartment of the flexible vessel, the second end of the tube being configured to pass through the opening of the connector, said tube carrying at least one sensor element. |
| Claim: |
19. The apparatus of claim 18, further including a flexible plastic material for forming a seal between the tube and the connector. |
| Claim: |
20. The apparatus of claim 19, wherein the vessel comprises a bag. |
| Claim: |
21. A probe assembly, comprising: a flexible bag having an interior surface bounding a passage extending between a first end and an opposing second end, the flexible bag being selectively movable between an extended position wherein the first end and the opposing second end are spaced apart and a collapsed position wherein the first end and the opposing second end are moved closer together relative to the extended position; a connector secured to the second end of the flexible bag, the connector having an opening extending therethrough that communicates with the passage of the flexible bag, a sealing layer removably covering the opening of the connector; and an elongated probe having a first end and an opposing second end, the second end of the probe being positioned within the passage of the flexible bag, the second end of the probe being configured to pass through the opening of the connector when the sealing layer is removed therefrom. |
| Claim: |
22. The probe assembly as recited in claim 21, further comprising a tubular coupler secured to a portion of the probe, wherein a portion of the probe extends through a tubular coupler. |
| Claim: |
23. The probe assembly as recited in claim 21, wherein at least a portion of the passage of the flexible bag forms a part of a sealed compartment, the second end of the probe being positioned within the sealed compartment. |
| Claim: |
24. The probe assembly as recited in claim 21, wherein the probe comprises an oxygen sensor or a pH sensor. |
| Claim: |
25. The probe assembly as recited in claim 21, further comprising a cover removably mounted on the connector and covering at least a portion of the sealing layer. |
| Claim: |
26. A probe assembly comprising: a flexible sleeve having an interior surface bounding a passage extending between a first end and an opposing second end; a connector secured to the second end of the flexible sleeve, the connector having an opening extending therethrough that communicates with the passage of the flexible sleeve, and an elongated probe having a first end and an opposing second end, the second end of the probe being positioned within the passage of the flexible sleeve and configured to pass through the opening of the connector. |
| Claim: |
27. The probe assembly of claim 26, further including a sealing layer removably covering the opening of the connector; and the second end of the probe is configured to pass through the opening of the connector when the sealing layer is removed therefrom. |
| Claim: |
28. The probe assembly of claim 26, further comprising a tubular coupler secured to the first end of the flexible sleeve or flexible bag, a portion of the probe extending through or being secured to the tubular coupler. |
| Claim: |
29. A bag for processing a fluid including the probe assembly of claim 26. |
| Claim: |
30. An apparatus for processing a fluid, comprising: a flexible vessel for receiving the fluid, the vessel including a connector having an opening; a flexible tube connected to the connector and including a passage; and a sensor adapted for passing through the opening of the connector and the passage of the tube for sensing a characteristic of the fluid. |
| Claim: |
31. The apparatus of claim 30, further including a sealing tube for sealing the opening between the sensor and the connector. |
| Current U.S. Class: |
206/216 |
| Current International Class: |
65; 01 |
| رقم الانضمام: |
edspap.20120152769 |
| قاعدة البيانات: |
USPTO Patent Applications |