Academic Journal
Deux nouveaux alcaloïdes quaternaires isolés à partir des feuilles du Strychnos usambarensis GILG du Rwanda: Nb-méthyl hydroxy-10 et hydroxy-11 usambarines
العنوان: | Deux nouveaux alcaloïdes quaternaires isolés à partir des feuilles du Strychnos usambarensis GILG du Rwanda: Nb-méthyl hydroxy-10 et hydroxy-11 usambarines The isolation and structure determination of two new quaternary alkaloids from Strychnos usambarensis GILG leaves of Rwanda: Nb-methyl-10- and 11-hydroxy-usambarine. |
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المؤلفون: | Caprasse, Maryse, Tavernier, Dirk, Angenot, Luc |
المصدر: | Journal de Pharmacie de Belgique, 38 (4), 211-218 (1983) |
بيانات النشر: | Nationale Pharmaceutique, 1983. |
سنة النشر: | 1983 |
مصطلحات موضوعية: | Strychnos usambarensis, Strychnos nigritana, Strychnos barteri, Strychnos tchibangensis, usambarine skeleton, hydroxy-usambarine, nigritanine, tchibangensine, dihydro-usambarensine, Physical, chemical, mathematical & earth Sciences, Chemistry, Life sciences, Phytobiology (plant sciences, forestry, mycology...), Human health sciences, Pharmacy, pharmacology & toxicology, Physique, chimie, mathématiques & sciences de la terre, Chimie, Sciences du vivant, Biologie végétale (sciences végétales, sylviculture, mycologie...), Sciences de la santé humaine, Pharmacie, pharmacologie & toxicologie |
الوصف: | Two new isomeric bis-indole alkaloids have been isolated from Strychnos usambarensis leaves. They are phenolic dimers of the "usambarine (usambarane) type" and correspond to the Nb-methyl-derivatives of 10- and 11-hydroxy-usambarine. The structure elucidation and the stereochemistry of these molecules are discussed from their spectroscopic properties (UV,IR,MS, CD , NMR). TLC comparison with quaternarized 10- and 11-hydroxy-usambarine provides a corroborative structural proof. The separation of the two alkaloids by "DCCC" (Droplet Counter current Chromatography) gives a new example of the application of this suitable technique for the separation of polar coumpounds that it is always very difficult to purify and separate. |
نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article peer reviewed |
اللغة: | French |
Relation: | urn:issn:0047-2166 |
URL الوصول: | https://orbi.uliege.be/handle/2268/40910 |
Rights: | open access http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsorb.40910 |
قاعدة البيانات: | ORBi |
الوصف غير متاح. |