Academic Journal

Deux nouveaux alcaloïdes quaternaires isolés à partir des feuilles du Strychnos usambarensis GILG du Rwanda: Nb-méthyl hydroxy-10 et hydroxy-11 usambarines

التفاصيل البيبلوغرافية
العنوان: Deux nouveaux alcaloïdes quaternaires isolés à partir des feuilles du Strychnos usambarensis GILG du Rwanda: Nb-méthyl hydroxy-10 et hydroxy-11 usambarines
The isolation and structure determination of two new quaternary alkaloids from Strychnos usambarensis GILG leaves of Rwanda: Nb-methyl-10- and 11-hydroxy-usambarine.
المؤلفون: Caprasse, Maryse, Tavernier, Dirk, Angenot, Luc
المصدر: Journal de Pharmacie de Belgique, 38 (4), 211-218 (1983)
بيانات النشر: Nationale Pharmaceutique, 1983.
سنة النشر: 1983
مصطلحات موضوعية: Strychnos usambarensis, Strychnos nigritana, Strychnos barteri, Strychnos tchibangensis, usambarine skeleton, hydroxy-usambarine, nigritanine, tchibangensine, dihydro-usambarensine, Physical, chemical, mathematical & earth Sciences, Chemistry, Life sciences, Phytobiology (plant sciences, forestry, mycology...), Human health sciences, Pharmacy, pharmacology & toxicology, Physique, chimie, mathématiques & sciences de la terre, Chimie, Sciences du vivant, Biologie végétale (sciences végétales, sylviculture, mycologie...), Sciences de la santé humaine, Pharmacie, pharmacologie & toxicologie
الوصف: Two new isomeric bis-indole alkaloids have been isolated from Strychnos usambarensis leaves. They are phenolic dimers of the "usambarine (usambarane) type" and correspond to the Nb-methyl-derivatives of 10- and 11-hydroxy-usambarine. The structure elucidation and the stereochemistry of these molecules are discussed from their spectroscopic properties (UV,IR,MS, CD , NMR). TLC comparison with quaternarized 10- and 11-hydroxy-usambarine provides a corroborative structural proof. The separation of the two alkaloids by "DCCC" (Droplet Counter current Chromatography) gives a new example of the application of this suitable technique for the separation of polar coumpounds that it is always very difficult to purify and separate.
نوع الوثيقة: journal article
http://purl.org/coar/resource_type/c_6501
article
peer reviewed
اللغة: French
Relation: urn:issn:0047-2166
URL الوصول: https://orbi.uliege.be/handle/2268/40910
Rights: open access
http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
رقم الانضمام: edsorb.40910
قاعدة البيانات: ORBi