Academic Journal
A standard numbering scheme for class C β-lactamases
| العنوان: | A standard numbering scheme for class C β-lactamases |
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| المؤلفون: | Mack, A. R., Barnes, M. D., Taracila, M. A., Hujer, A. M., Hujer, K. M., Cabot, G., Feldgarden, M., Haft, D. H., Klimke, W., Van Den Akker, F., Vila, A. J., Smania, A., Haider, S., Papp-Wallace, K. M., Bradford, P. A., Rossolini, G. M., Docquier, Jean-Denis, Frère, Jean-Marie, Galleni, Moreno, Hanson, N. D., Oliver, A., Plésiat, P., Poirel, L., Nordmann, P., Palzkill, T. G., Jacoby, G. A., Bush, K., Bonomo, R. A. |
| المصدر: | Antimicrobial Agents and Chemotherapy, 64 (3) (2020) |
| بيانات النشر: | American Society for Microbiology, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Amino acid numbering, AmpC, Beta-lactamases, Class C beta-lactamase, Conserved residue, Nomenclature, Structure-activity relationships, Article, Life sciences, Microbiology, Sciences du vivant, Microbiologie |
| الوصف: | Unlike for classes A and B, a standardized amino acid numbering scheme has not been proposed for the class C (AmpC) β-lactamases, which complicates communication in the field. Here, we propose a scheme developed through a collaborative approach that considers both sequence and structure, preserves traditional numbering of catalytically important residues (Ser64, Lys67, Tyr150, and Lys315), is adaptable to new variants or enzymes yet to be discovered and includes a variation for genetic and epidemiological applications. Copyright © 2020 American Society for Microbiology. All Rights Reserved. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501 article peer reviewed |
| اللغة: | English |
| Relation: | urn:issn:0066-4804; urn:issn:1098-6596 |
| DOI: | 10.1128/AAC.01841-19 |
| URL الوصول: | https://orbi.uliege.be/handle/2268/252541 |
| Rights: | restricted access http://purl.org/coar/access_right/c_16ec info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsorb.252541 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1128/AAC.01841-19 |
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