Electronic Resource
The dental proteome of Homo antecessor
| العنوان: | The dental proteome of Homo antecessor |
|---|---|
| المؤلفون: | Universitat Rovira i Virgili, Welker F; Ramos-Madrigal J; Gutenbrunner P; Mackie M; Tiwary S; Rakownikow Jersie-Christensen R; Chiva C; Dickinson MR; Kuhlwilm M; de Manuel M; Gelabert P; Martinón-Torres M; Margvelashvili A; Arsuaga JL; Carbonell E; Marques-Bonet T; Penkman K; Sabidó E; Cox J; Olsen JV; Lordkipanidze D; Racimo F; Lalueza-Fox C; Bermúdez de Castro JM; Willerslev E; Cappellini E |
| المصدر: | Nature; 10.1038/s41586-020-2153-8; Nature. 580 (7802): 235-238 |
| بيانات النشر: | 2020 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | © 2020, The Author(s), under exclusive licence to Springer Nature Limited. The phylogenetic relationships between hominins of the Early Pleistocene epoch in Eurasia, such as Homo antecessor, and hominins that appear later in the fossil record during the Middle Pleistocene epoch, such as Homo sapiens, are highly debated1–5. For the oldest remains, the molecular study of these relationships is hindered by the degradation of ancient DNA. However, recent research has demonstrated that the analysis of ancient proteins can address this challenge6–8. Here we present the dental enamel proteomes of H. antecessor from Atapuerca (Spain)9,10 and Homo erectus from Dmanisi (Georgia)1, two key fossil assemblages that have a central role in models of Pleistocene hominin morphology, dispersal and divergence. We provide evidence that H. antecessor is a close sister lineage to subsequent Middle and Late Pleistocene hominins, including modern humans, Neanderthals and Denisovans. This placement implies that the modern-like face of H. antecessor—that is, similar to that of modern humans—may have a considerably deep ancestry in the genus Homo, and that the cranial morphology of Neanderthals represents a derived form. By recovering AMELY-specific peptide sequences, we also conclude that the H. antecessor molar fragment from Atapuerca that we analysed belonged to a male individual. Finally, these H. antecessor and H. erectus fossils preserve evidence of enamel proteome phosphorylation and proteolytic digestion that occurred in vivo during tooth formation. Our results provide important insights into the evolutionary relationships between H. antecessor and other hominin groups, and pave the way for future studies using enamel proteomes to investigate hominin biology across the existence of the ge |
| مصطلحات الفهرس: | Multidisciplinary,Multidisciplinary Sciences, Zootecnia / recursos pesqueiros, Sociology, Sociología, Social statistics and informatics, Science and technology studies, Saúde coletiva, Química, Psicología, Multidisciplinary sciences, Multidisciplinary, Medicina veterinaria, Medicina iii, Medicina ii, Medicina i, Media studies and communication, Matemática / probabilidade e estatística, Interdisciplinary research in the social sciences, Interdisciplinar, Human geography and urban studies, Geografía, Geociências, General o multidisciplinar, General medicine, Farmacia, Environmental studies, Engenharias iii, Engenharias ii, Engenharias i, Economics, Economia, Demography, Ciencias sociales, Ciencias humanas, Ciências biológicas iii, Ciências biológicas ii, Ciências biológicas i, Ciências ambientais, Ciências agrárias i, Ciência política e relações internacionais, Biotecnología, Biodiversidade, Astronomia / física, Arquitetura e urbanismo, Archaeology, Anthropology, Journal Publications |
| URL: | |
| الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| Other Numbers: | RIV oai:urv.cat:imarina:6238554 1443573310 |
| المصدر المساهم: | UNIVERSITAT ROVIRA I VIRGILI BIBLIOTECA From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1443573310 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |