Electronic Resource
A membrane-bound ankyrin repeat protein confers race-specific leaf rust disease resistance in wheat
| العنوان: | A membrane-bound ankyrin repeat protein confers race-specific leaf rust disease resistance in wheat |
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| المؤلفون: | Kolodziej, Markus C; https://orcid.org/0000-0003-3155-2935, Singla, Jyoti, Sánchez-Martín, Javier; https://orcid.org/0000-0002-0284-7219, Zbinden, Helen, Šimková, Hana; https://orcid.org/0000-0003-4159-7619, Karafiátová, Miroslava; https://orcid.org/0000-0003-1177-6472, Doležel, Jaroslav; https://orcid.org/0000-0002-6263-0492, Gronnier, Julien; https://orcid.org/0000-0002-1429-0542, Poretti, Manuel; https://orcid.org/0000-0001-6915-2238, Glauser, Gaétan, Zhu, Wangsheng; https://orcid.org/0000-0001-7773-3438, Köster, Philipp; https://orcid.org/0000-0002-1359-822X, Zipfel, Cyril; https://orcid.org/0000-0003-4935-8583, Wicker, Thomas; https://orcid.org/0000-0002-6777-7135, Krattinger, Simon G; https://orcid.org/0000-0001-6912-7411, Keller, Beat; https://orcid.org/0000-0003-2379-9225 |
| المصدر: | Kolodziej, Markus C; Singla, Jyoti; Sánchez-Martín, Javier; Zbinden, Helen; Šimková, Hana; Karafiátová, Miroslava; Doležel, Jaroslav; Gronnier, Julien; Poretti, Manuel; Glauser, Gaétan; Zhu, Wangsheng; Köster, Philipp; Zipfel, Cyril; Wicker, Thomas; Krattinger, Simon G; Keller, Beat (2021). A membrane-bound ankyrin repeat protein confers race-specific leaf rust disease resistance in wheat. Nature Communications, 12:956. |
| بيانات النشر: | Nature Publishing Group 2021-12-01 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Plasma membrane-associated and intracellular proteins and protein complexes play a pivotal role in pathogen recognition and disease resistance signaling in plants and animals. The two predominant protein families perceiving plant pathogens are receptor-like kinases and nucleotide binding-leucine-rich repeat receptors (NLR), which often confer race-specific resistance. Leaf rust is one of the most prevalent and most devastating wheat diseases. Here, we clone the race-specific leaf rust resistance gene Lr14a from hexaploid wheat. The cloning of Lr14a is aided by the recently published genome assembly of ArinaLrFor, an Lr14a-containing wheat line. Lr14a encodes a membrane-localized protein containing twelve ankyrin (ANK) repeats and structural similarities to Ca2+-permeable non-selective cation channels. Transcriptome analyses reveal an induction of genes associated with calcium ion binding in the presence of Lr14a. Haplotype analyses indicate that Lr14a-containing chromosome segments were introgressed multiple times into the bread wheat gene pool, but we find no variation in the Lr14a coding sequence itself. Our work demonstrates the involvement of an ANK-transmembrane (TM)-like type of gene family in race-specific disease resistance in wheat. This forms the basis to explore ANK-TM-like genes in disease resistance breeding. |
| مصطلحات الفهرس: | Department of Plant and Microbial Biology, Zurich-Basel Plant Science Center, 580 Plants (Botany), General Biochemistry, Genetics and Molecular Biology, General Physics and Astronomy, General Chemistry, Journal Article, PeerReviewed, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion |
| URL: | 10.1038/s41467-020-20777-x |
| الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess Creative Commons: Attribution 4.0 International (CC BY 4.0) http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf info:doi/10.5167/uzh-199900 English |
| Other Numbers: | CHUZH oai:www.zora.uzh.ch:199900 https://www.zora.uzh.ch/id/eprint/199900/1/s41467-020-20777-x.pdf info:doi/10.5167/uzh-199900 info:doi/10.1038/s41467-020-20777-x urn:issn:2041-1723 1443036429 |
| المصدر المساهم: | HAUPTBIBLIOTHEK UNIV OF ZURICH From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1443036429 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |