Electronic Resource
Interactions Between Peptide Assemblies and Proteins for Medicine
| العنوان: | Interactions Between Peptide Assemblies and Proteins for Medicine |
|---|---|
| المؤلفون: | Ministerio de Ciencia e Innovación (España), Università degli studi di Trieste, Agencia Estatal de Investigación (España), European Commission, Mañas-Torres, Mari C., Illescas-López, Sara, Gavira Gallardo, J. A., Cienfuegos, Luis Álvarez de, Marchesan, Silvia |
| بيانات النشر: | Wiley-VCH 2022-06 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Peptide assembly is attractive not only to develop biotechnological tools and smart nanomaterials, but also to treat pathologies in new ways. This Review focuses on recent progress made in the exciting area pertaining the interaction between peptide assemblies and proteins. Earlier works aimed to identify proteins able to bind peptide assemblies for therapeutics’ delivery and biocompatible scaffolds. Recent advancements cover more applications that go beyond tissue regeneration and biomaterials. On one hand, self-assembling peptides interacting with proteins can inhibit pathological amyloid fibrillation, or boost the immune response to vaccines. On the other, they have been exploited to promote protein crystallization, also for therapeutics’ delivery. As research advances in this exciting area, it opens the way towards a qualitative leap in the clinical translation of supramolecular medicinal chemistry to creatively tackle unmet challenges of modern disease treatment and prevention. |
| مصطلحات الفهرس: | Biomaterials, Peptide, Proteins, Self-assembly, Vaccines, artículo de revisión |
| URL: | Publisher's version Sí info:eu-repo/grantAgreement/MCIN/AEI/10.13039/501100011033 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-116261GB-I00/ES/APLICACIONES BIOTECNOLOGICAS DE CRISTALES PROTEICOS info:eu-repo/grantAgreement/MINECO//PRE2018-083773 |
| الاتاحة: | Open access content. Open access content https://creativecommons.org/licenses/by/4.0 openAccess |
| Other Numbers: | CTK oai:digital.csic.es:10261/356915 Israel Journal of Chemistry 62: e202200018 (2022) 1442725665 |
| المصدر المساهم: | CSIC From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1442725665 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |