Electronic Resource
Differential efficacy with epidural blood and fibrin patches for the treatment of post‐dural puncture headache
| العنوان: | Differential efficacy with epidural blood and fibrin patches for the treatment of post‐dural puncture headache |
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| المؤلفون: | Universidad de Sevilla. Departamento de Cirugía, López Millán, Jose Manuel, Ordóñez Fernández, Antonio, Muriel Fernández, Jorge, Dueñas Díez, José Luis |
| بيانات النشر: | Wiley 2024 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Background: Accidental dural puncture (ADP) is the most frequent major complication when performing an epidural procedure in obstetrics. Consequently, loss of pressure in the cerebrospinal fluid (CSF) leads to the development of postdural puncture headache (PDPH), which occurs in 16%–86% of cases. To date, the efficacy of epidural fibrin patches (EFP) has not been evaluated in a controlled clinical trial, nor in comparative studies with epidural blood patches (EBP). Methods: The objective of the present study was to compare the efficacy of EFP with respect to EBP for the treatment of refractory accidental PDPH. This prospective, randomized, open-label, parallel, comparative study included 70 puerperal women who received an EBP or EFP (35 in each group) after failure of the conventional analgesic treatment for accidental PDPH in a hospital. Results: A higher percentage of women with EFP than EBP achieved complete PDPH relief after 2 (97.1% vs. 54.3%) and 12h (100.0% vs. 65.7%) of the patch injection. The percentage of patients who needed rescue analgesia was significantly lower with EFP after 2 (2.9% vs. 48.6%) and 12h (0.0% vs. 37.1%). After 24h, PDPH was resolved in all women who received EFP. The recurrence of PDPH was reported in one woman from the EBP group (2.9%), who subsequently required a second patch. The mean length of hospital stay was significantly lower with EFP (3.9days) than EBP (5.9days). Regarding satisfaction, the mean value (Likert scale) was significantly higher with EFP (4.7 vs. 3.0). Conclusions: EFP provided better outcomes than EBP for the treatment of obstetric PDPH in terms of efficacy, safety, and patient satisfaction. |
| مصطلحات الفهرس: | Blood, dural, Epidural, Fibrin, Headache, Patch, Puncture, info:eu-repo/semantics/article |
| URL: | |
| الاتاحة: | Open access content. Open access content http://creativecommons.org/licenses/by-nc-nd/4.0 info:eu-repo/semantics/openAccess Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
| ملاحظة: | English |
| Other Numbers: | SUE oai:idus.us.es:11441/158816 1530-7085 10.1111/papr.13318 1442718777 |
| المصدر المساهم: | UNIV DE SEVILLA From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1442718777 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |