Electronic Resource
Long-term outcome of COVID-19 patients treated with helmet noninvasive ventilation vs. high-flow nasal oxygen: a randomized trial
| العنوان: | Long-term outcome of COVID-19 patients treated with helmet noninvasive ventilation vs. high-flow nasal oxygen: a randomized trial |
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| المؤلفون: | Michi, Teresa, Mattana, Chiara, Menga, Luca Salvatore, Bocci, Maria Grazia, Cesarano, Melania, Rosà, Tommaso, Gualano, Maria Rosaria, Montomoli, Jonathan, Spadaro, Savino, Tosato, Matteo, Rota, Elisabetta, Landi, Francesco, Cutuli, Salvatore Lucio, Tanzarella, Eloisa S., Pintaudi, Gabriele, Piervincenzi, Edoardo, Bello, Giuseppe, Tonetti, Tommaso, Rucci, Paola, De Pascale, Gennaro, Maggiore, Salvatore M., Grieco, Domenico Luca, Conti, Giorgio, Antonelli, Massimo, Maviglia, Riccardo, Mercurio, Giovanna, De Santis, Paolo, Pennisi, Mariano Alberto, Anzellotti, Gian Marco, Torrini, Flavia, Rubino, Carlotta, Morena, Tony Christian, Gennenzi, Veronica, Postorino, Stefania, Vargas, Joel, Filetici, Nicoletta, Settanni, Donatella, Durante, Miriana, Cascarano, Laura, Di Muro, Mariangela, Scarascia, Roberta, Bitondo, Maria Maddalena, Murdolo, Martina, Mele, Alessandro, Silva, Serena, Zaccone, Carmelina, Pozzana, Francesca, Maccaglia, Alessio, Savino, Martina, Potalivo, Antonella, Ceccaroni, Francesca, Scavone, Angela, Lombardi, Gianmarco, Montini, Luca, Dell'Anna, Antonio Maria, Volta, Carlo Alberto, Ranieri, Vito M., Falò, Giulia, Carelli, Simone, Natalini, Daniele, Berardi, Cecilia, Delle Cese, Luca, Vetrugno, Luigi, Balzani, Eleonora, Null, Null, Menga, Luca S., Landi, Francesco (ORCID:0000-0002-3472-1389), Cutuli, Salvatore L., Bello, Giuseppe (ORCID:0000-0003-2648-7235), De Pascale, Gennaro (ORCID:0000-0002-8255-0676), Grieco, Domenico Luca (ORCID:0000-0002-4557-6308), Conti, Giorgio (ORCID:0000-0002-8566-9365), Antonelli, Massimo (ORCID:0000-0003-3007-1670), Pennisi, Mariano Alberto (ORCID:0000-0001-8761-5144), Morena, Tony C., Montini, Luca (ORCID:0000-0003-4602-5134), Dell’Anna, Antonio Maria |
| بيانات النشر: | BMC 2023 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | BackgroundLong-term outcomes of patients treated with helmet noninvasive ventilation (NIV) are unknown: safety concerns regarding the risk of patient self-inflicted lung injury and delayed intubation exist when NIV is applied in hypoxemic patients. We assessed the 6-month outcome of patients who received helmet NIV or high-flow nasal oxygen for COVID-19 hypoxemic respiratory failure.MethodsIn this prespecified analysis of a randomized trial of helmet NIV versus high-flow nasal oxygen (HENIVOT), clinical status, physical performance (6-min-walking-test and 30-s chair stand test), respiratory function and quality of life (EuroQoL five dimensions five levels questionnaire, EuroQoL VAS, SF36 and Post-Traumatic Stress Disorder Checklist for the DSM) were evaluated 6 months after the enrollment.ResultsAmong 80 patients who were alive, 71 (89%) completed the follow-up: 35 had received helmet NIV, 36 high-flow oxygen. There was no inter-group difference in any item concerning vital signs (N = 4), physical performance (N = 18), respiratory function (N = 27), quality of life (N = 21) and laboratory tests (N = 15). Arthralgia was significantly lower in the helmet group (16% vs. 55%, p = 0.002). Fifty-two percent of patients in helmet group vs. 63% of patients in high-flow group had diffusing capacity of the lungs for carbon monoxide < 80% of predicted (p = 0.44); 13% vs. 22% had forced vital capacity < 80% of predicted (p = 0.51). Both groups reported similar degree of pain (p = 0.81) and anxiety (p = 0.81) at the EQ-5D-5L test; the EQ-VAS score was similar in the two groups (p = 0.27). Compared to patients who successfully avoided invasive mechanical ventilation (54/71, 76%), intubated patients (17/71, 24%) had significantly worse pulmonary function (median diffusing capacity of the lungs for carbon monoxide 66% [Interquartile range: 47-77] of predicted vs. 80% [71-88], p = 0.005) and decreased quality of life (EQ-VAS: 70 [53-70] vs. 80 [70-83], p = 0.01).ConclusionsIn |
| مصطلحات الفهرس: | Acute respiratory failure, COVID-19, Helmet, High-flow nasal oxygen, Noninvasive ventilation, Patient self-inflicted lung injury (P-SILI), Settore MED/41 - ANESTESIOLOGIA, info:eu-repo/semantics/article |
| URL: | info:eu-repo/semantics/altIdentifier/pmid/37208787 info:eu-repo/semantics/altIdentifier/wos/WOS:000991016400001 volume:11 issue:1 firstpage:N/A lastpage:N/A issueyear:2023 journal:JOURNAL OF INTENSIVE CARE |
| الاتاحة: | Open access content. Open access content |
| ملاحظة: | English |
| Other Numbers: | SYC oai:publicatt.unicatt.it:10807/262675 10.1186/s40560-023-00669-0 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85160058986 1439663163 |
| المصدر المساهم: | UNIV CATTOLICA DEL SACRO CUORE From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1439663163 |
| قاعدة البيانات: | OAIster |
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