Electronic Resource

Evaluation of clinical and mpMRI findings of irreversible electroporation therapy for the treatment of localized prostate cancer: Preliminary results

التفاصيل البيبلوغرافية
العنوان: Evaluation of clinical and mpMRI findings of irreversible electroporation therapy for the treatment of localized prostate cancer: Preliminary results
المؤلفون: Tarhan, Nefise Çağla, Adsan, Öztuğ, Kızıl, P. G., Altan, Ş. A.
بيانات النشر: AVES 2021-09-11T15:19:44Z 2021-09-11T15:19:44Z 2021
نوع الوثيقة: Electronic Resource
مستخلص: Objective: To evaluate early clinical and multiparametric prostate magnetic resonance imaging (mpMRI) results of irreversible electroporation (IRE) efficiency in treatment of localized prostate cancer. Material and methods: For the patients in whom IRE was performed for local ablation, mpMRI was used for the sixth month follow-up. These images were compared with the mpMRI images obtained before the pro-cedure. We performed transperineal fusion biopsy to patients with diagnosis of localized prostate cancer. We treated the eligible ones with IRE. Six of them have completed their 6-month follow-up period. We compared preoperative prostate specific antigen (PSA), international prostate symptom score, international index of erectile function (IIEF), and mpMRI of these patients with those obtained at the sixth month of follow-up. Side effects experienced by the patients were evaluated as well. Results: We had 10 patients who received IRE treatment. Six patients completed their sixth month-follow-up and came for control visits. At the end of 6 months, the mean decrease in PSA level was 73%. IIEF results were seen not to have changed significantly. On mpMRI, diffusion restriction was seen to have disappeared except for one patient, and Prostate Imaging Reporting Data System scores were decreased. Conclusion: We concluded that early clinical and mpMRI results for IRE in the focal ablative treatment of localized prostate cancer were gratifying. As an ambulatory procedure with a low incidence of side effects, we look forward to seeing the long-term results of IRE treatment. © 2021 by Turkish Association of Urology.
مصطلحات الفهرس: Focal ablation, IRE, Prostate cancer, Treatment, Article
URL: https://hdl.handle.net/20.500.11851/5714
https://doi.org/10.5152/tud.2021.21040
Turkish Journal of Urology
Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
الاتاحة: Open access content. Open access content
none
ملاحظة: English
Other Numbers: TRTET oai:gcris.etu.edu.tr:20.500.11851/5714
2149-3235
47
4
299
304
WOS:000678176700010
2-s2.0-85111149954
10.5152/tud.2021.21040
Q3
1426275697
المصدر المساهم: TOBB EKONOMI VE TEKNOLOJI UNIV
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رقم الانضمام: edsoai.on1426275697
قاعدة البيانات: OAIster