Electronic Resource
Neuroanatomical and neurocognitive changes associated with subjective cognitive decline
| العنوان: | Neuroanatomical and neurocognitive changes associated with subjective cognitive decline |
|---|---|
| المؤلفون: | Universidade de Santiago de Compostela. Departamento de Psicoloxía Clínica e Psicobioloxía, Universidade de Santiago de Compostela. Departamento de Psicoloxía Evolutiva e da Educación, Rivas Fernández, Miguel Ángel, Lindín, Mónica, Zurrón, Montserrat, Díaz Fernández, Fernando, Lojo-Seoane, Cristina, Pereiro Rozas, Arturo José, Galdo-Alvarez, Santiago |
| بيانات النشر: | Frontiers Media 2023 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Introduction: Subjective Cognitive Decline (SCD) can progress to mild cognitive impairment (MCI) and Alzheimer’s disease (AD) dementia and thus may represent a preclinical stage of the AD continuum. However, evidence about structural changes observed in the brain during SCD remains inconsistent. Materials and methods: This cross-sectional study aimed to evaluate, in subjects recruited from the CompAS project, neurocognitive and neurostructural differences between a group of forty-nine control subjects and forty-nine individuals who met the diagnostic criteria for SCD and exhibited high levels of subjective cognitive complaints (SCCs). Structural magnetic resonance imaging was used to compare neuroanatomical differences in brain volume and cortical thickness between both groups. Results: Relative to the control group, the SCD group displayed structural changes involving frontal, parietal, and medial temporal lobe regions of critical importance in AD etiology and functionally related to several cognitive domains, including executive control, attention, memory, and language. Conclusion: Despite the absence of clinical deficits, SCD may constitute a preclinical entity with a similar (although subtle) pattern of neuroanatomical changes to that observed in individuals with amnestic MCI or AD dementia |
| مصطلحات الفهرس: | Alzheimer’s disease, Subjective cognitive decline (SCD), Structural magnetic resonance imaging, Brain structural changes, Subjective cognitive complaints, journal article |
| URL: | |
| الاتاحة: | Open access content. Open access content open access © 2023 Rivas-Fernández, Lindín, Zurrón, Díaz, Lojo-Seoane, Pereiro and Galdo-Álvarez. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). (https://creativecommons.org/licenses/by/4.0/) |
| ملاحظة: | English |
| Other Numbers: | ESUSC oai:minerva.usc.es:10347/30704 Rivas-Fernández MÁ, Lindín M, Zurrón M, Díaz F, Lojo-Seoane C, Pereiro AX and Galdo-Álvarez S (2023) Neuroanatomical and neurocognitive changes associated with subjective cognitive decline. Front. Med. 10:1094799 10.3389/fmed.2023.1094799 2296-858X 1401001473 |
| المصدر المساهم: | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1401001473 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |