Electronic Resource
Effect modification of an effective transdiagnostic cognitive behavioral psychotherapy in youths with common mental health problems:Secondary analyses of the randomized mind-my-mind trial
| العنوان: | Effect modification of an effective transdiagnostic cognitive behavioral psychotherapy in youths with common mental health problems:Secondary analyses of the randomized mind-my-mind trial |
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| المؤلفون: | Rimvall, Martin Køster, Vassard, Ditte, Nielsen, Sabrina Mai, Wolf, Rasmus Trap, Plessen, Kerstin Jessica, Bilenberg, Niels, Thomsen, Per Hove, Thastum, Mikael, Neumer, Simon-Peter, Puggaard, Louise Berg, Pedersen, Mette Maria Agner, Pagsberg, Anne Katrine, Silverman, Wendy K, Correll, Christoph U, Christensen, Robin, Jeppesen, Pia |
| المصدر: | Rimvall , M K , Vassard , D , Nielsen , S M , Wolf , R T , Plessen , K J , Bilenberg , N , Thomsen , P H , Thastum , M , Neumer , S-P , Puggaard , L B , Pedersen , M M A , Pagsberg , A K , Silverman , W K , Correll , C U , Christensen , R & Jeppesen , P 2023 , ' Effect modification of an effective transdiagnostic cognitive behavioral psychotherapy in youths with common mental health problems : Secondary analyses of the randomized mind-my-mind trial ' , European Neuropsychopharmacology , vol. 74 , pp. 64-75 . |
| بيانات النشر: | 2023 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Mind My Mind (MMM) cognitive behavioral therapy (CBT) manualized treatment is effective in the management of common emotional and behavioral mental health problems in youth, yet not all individuals respond satisfactorily to treatment. This study explored potential effect modifiers, i.e., baseline factors associated with a differential treatment effect. We conducted secondary effect modifier analyses with MMM trial data, which involved randomization of 396 youths aged 6–16 years to either MMM CBT treatment (9–13 sessions) or management as usual in local community settings. We examined sociodemographic- (sex, age, family composition, ethnicity, parental education, and income) and clinical variables (mental disorders and duration of mental health problems) as potential effect modifiers of the a) change in parent-rated impact of mental health problems measured by the Strengths and Difficulties Questionnaire (SDQ) or b) response (reduction of ≥1 on SDQ-impact). In intention-to-treat analyses, superior treatment (net) benefits from the MMM intervention were found among youths who met criteria for any mental disorder at baseline (-1.25 [95%CI: -1.67;-0.82]) compared to youths that did not meet diagnostic criteria (-0.22 [95%CI:-1.09;0.65]). Comorbidity vs no comorbidity (-1.84 [95%CI:-2.58;-1.10] vs -0.72 [95%CI:-1.15;-0.29]) and longer duration of untreated mental health problems, i.e., more vs less than 6 months (-1.16 [95%CI:-1.55;-0.78] vs 0.43 [95%CI:-1.01;1.86]) were also associated with superior treatment benefits. The sociodemographic factors were not associated with differential treatment effects in the intention-to-treat analyses. These findings suggest that community-based programs like the MMM are well-suited for youths with substantial mental health problems. Clinical Trials Identifier: NCT03535805 Mind My Mind (MMM) cognitive behavioral therapy (CBT) manualized treatment is effective in the management of common emotional and behavioral mental health problems in youth, yet not all individuals respond satisfactorily to treatment. This study explored potential effect modifiers, i.e., baseline factors associated with a differential treatment effect. We conducted secondary effect modifier analyses with MMM trial data, which involved randomization of 396 youths aged 6-16 years to either MMM CBT treatment (9-13 sessions) or management as usual in local community settings. We examined sociodemographic- (sex, age, family composition, ethnicity, parental education, and income) and clinical variables (mental disorders and duration of mental health problems) as potential effect modifiers of the a) change in parent-rated impact of mental health problems measured by the Strengths and Difficulties Questionnaire (SDQ) or b) response (reduction of ≥1 on SDQ-impact). In intention-to-treat analyses, superior treatment (net) benefits from the MMM intervention were found among youths who met criteria for any mental disorder at baseline (-1.25 [95%CI: -1.67;-0.82]) compared to youths that did not meet diagnostic criteria (-0.22 [95%CI:-1.09;0.65]). Comorbidity vs no comorbidity (-1.84 [95%CI:-2.58;-1.10] vs -0.72 [95%CI:-1.15;-0.29]) and longer duration of untreated mental health problems, i.e., more vs less than 6 months (-1.16 [95%CI:-1.55;-0.78] vs 0.43 [95%CI:-1.01;1.86]) were also associated with superior treatment benefits. The sociodemographic factors were not associated with differential treatment effects in the intention-to-treat analyses. These findings suggest that community-based programs like the MMM are well-suited for youths with substantial mental health problems. Clinical Trials Identifier: NCT03535805. |
| مصطلحات الفهرس: | article |
| URL: | |
| الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| Other Numbers: | DAV oai:pure.atira.dk:publications/944a28c2-6869-4765-b265-36f137fc247d 1397307005 |
| المصدر المساهم: | UNIV OF COPENHAGEN From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1397307005 |
| قاعدة البيانات: | OAIster |
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