Electronic Resource
Biological Predictors of Treatment Response in Adult Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review
العنوان: | Biological Predictors of Treatment Response in Adult Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review |
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المؤلفون: | Capuzzi, E, Caldiroli, A, Auxilia, A, Borgonovo, R, Capellazzi, M, Clerici, M, Buoli, M, Capuzzi E., Caldiroli A., Auxilia A. M., Borgonovo R., Capellazzi M., Clerici M., Buoli M. |
بيانات النشر: | MDPI country:CH 2022 |
نوع الوثيقة: | Electronic Resource |
مستخلص: | Background: Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent condition with onset in childhood and in many cases persisting into adulthood. Even though an increasing number of studies have investigated the efficacy of pharmacotherapy in the management of adult ADHD, few authors have tried to identify the biological predictors of treatment response. Objectives: To summarize the available data about the biological markers of treatment response in adults affected by ADHD. Methods: A search on the main biomedical and psychological archives (PubMed, Embase, Scopus, and PsycINFO) was performed. Manuscripts in English, published up to May 2022 and having the biological predictors of treatment response in adults with ADHD as their main topic, were included. Results: A total of 3855 articles was screened. Twenty-two articles were finally included. Most of the manuscripts studied neuroimaging and electrophysiological factors as potential predictors of treatment response in adult ADHD patients. No reliable markers were identified until now. Promising findings on this topic regard genetic polymorphisms in snap receptor (SNARE) proteins and default mode network-striatum connectivity. Conclusions: Even though some biological markers seem promising for the prediction of treatment response in adults affected by ADHD, further studies are needed to confirm the available data in the context of precision medicine. |
مصطلحات الفهرس: | adult, attention-deficit/hyperactivity disorder (ADHD), marker, outcome, treatment response, info:eu-repo/semantics/article |
URL: | info:eu-repo/semantics/altIdentifier/wos/WOS:000873320700001 volume:12 issue:10 journal:JOURNAL OF PERSONALIZED MEDICINE |
الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
ملاحظة: | ELETTRONICO English |
Other Numbers: | ITBAO oai:boa.unimib.it:10281/425560 10.3390/jpm12101742 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85140645885 1383765899 |
المصدر المساهم: | BICOCCA OPEN ARCH From OAIster®, provided by the OCLC Cooperative. |
رقم الانضمام: | edsoai.on1383765899 |
قاعدة البيانات: | OAIster |
الوصف غير متاح. |