Electronic Resource

Biological Predictors of Treatment Response in Adult Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review

التفاصيل البيبلوغرافية
العنوان: Biological Predictors of Treatment Response in Adult Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review
المؤلفون: Capuzzi, E, Caldiroli, A, Auxilia, A, Borgonovo, R, Capellazzi, M, Clerici, M, Buoli, M, Capuzzi E., Caldiroli A., Auxilia A. M., Borgonovo R., Capellazzi M., Clerici M., Buoli M.
بيانات النشر: MDPI country:CH 2022
نوع الوثيقة: Electronic Resource
مستخلص: Background: Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent condition with onset in childhood and in many cases persisting into adulthood. Even though an increasing number of studies have investigated the efficacy of pharmacotherapy in the management of adult ADHD, few authors have tried to identify the biological predictors of treatment response. Objectives: To summarize the available data about the biological markers of treatment response in adults affected by ADHD. Methods: A search on the main biomedical and psychological archives (PubMed, Embase, Scopus, and PsycINFO) was performed. Manuscripts in English, published up to May 2022 and having the biological predictors of treatment response in adults with ADHD as their main topic, were included. Results: A total of 3855 articles was screened. Twenty-two articles were finally included. Most of the manuscripts studied neuroimaging and electrophysiological factors as potential predictors of treatment response in adult ADHD patients. No reliable markers were identified until now. Promising findings on this topic regard genetic polymorphisms in snap receptor (SNARE) proteins and default mode network-striatum connectivity. Conclusions: Even though some biological markers seem promising for the prediction of treatment response in adults affected by ADHD, further studies are needed to confirm the available data in the context of precision medicine.
مصطلحات الفهرس: adult, attention-deficit/hyperactivity disorder (ADHD), marker, outcome, treatment response, info:eu-repo/semantics/article
URL: https://hdl.handle.net/10281/425560
info:eu-repo/semantics/altIdentifier/wos/WOS:000873320700001
volume:12
issue:10
journal:JOURNAL OF PERSONALIZED MEDICINE
الاتاحة: Open access content. Open access content
info:eu-repo/semantics/openAccess
ملاحظة: ELETTRONICO
English
Other Numbers: ITBAO oai:boa.unimib.it:10281/425560
10.3390/jpm12101742
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85140645885
1383765899
المصدر المساهم: BICOCCA OPEN ARCH
From OAIster®, provided by the OCLC Cooperative.
رقم الانضمام: edsoai.on1383765899
قاعدة البيانات: OAIster