Electronic Resource
Factors Associated With Functional Decline in Hand and Hip/Knee Osteoarthritis After One Year: Data From a Population-Based Study
| العنوان: | Factors Associated With Functional Decline in Hand and Hip/Knee Osteoarthritis After One Year: Data From a Population-Based Study |
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| المؤلفون: | Eposa Research Group |
| المصدر: | Vrije Universiteit Amsterdam Repository |
| بيانات النشر: | 2021 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | OBJECTIVE: The study investigated factors that together with hand or hip/knee osteoarthritis (OA) could contribute to functional decline over a year's time in elderly individuals.METHODS: The data of 1,886 individuals between the ages of 65-85 in a prospective, observational population-based study with 12-18 month follow-up in the context of the European Project on OSteoArthritis were analyzed. The outcome measures were self-reported hand and hip/knee functional decline evaluated using a Minimal Clinically Important Difference of 4 on the AUStralian/CANadian hand OA Index and of 2 on the Western Ontario and McMaster Universities hip/knee OA physical function subscales, both normalized to 0-100. Using regression models adjusted for sex, age, country, and education level, the baseline factors considered were: clinical hand or hip/knee OA, pain, analgesic/anti-inflammatory medications, comorbidities, social isolation, income, walking time, grip strength, physical activity time, and medical/social care.RESULTS: After a year, 453 participants were identified as having "worse" hand functionality and 1,389 as "not worse". Hand OA, anxiety, walking time and grip strength were risk factors for hand functional decline; pain was a confounder of the effect of hand OA. Analgesic/anti-inflammatory medications mediated the combined effect of hip/knee OA+pain on functional decline in the 554 individuals classified as having "worse" hip/knee functionality and the 1,291 "not worse" persons. Peripheral artery disease, obesity, and cognitive impairment were other baseline risk factors.CONCLUSION: Study findings showed that together with emotional status, chronic physical and cognitive conditions, OA affects hand and hip/knee functional decline. |
| مصطلحات الفهرس: | SDG 3 - Good Health and Well-being, Article |
| DOI: | 10.1002.acr.24404 |
| URL: | |
| الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | Arthritis Care & Research vol.73 (2021) nr.9 p.1343-1353 [ISSN 2151-464X] English |
| Other Numbers: | NLVRU oai:research.vu.nl:publications/090528fc-6a1c-440b-8a50-f48a7f79f047 DOI: 10.1002/acr.24404 1378930077 |
| المصدر المساهم: | VRIJE UNIVERSITEIT AMSTERDAM From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1378930077 |
| قاعدة البيانات: | OAIster |
| DOI: | 10.1002.acr.24404 |
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