Electronic Resource
An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International
| العنوان: | An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International |
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| المؤلفون: | Mueller, Roman-Ulrich, Messchendorp, A. Lianne, Birn, Henrik, Capasso, Giovambattista, Cornec-Le Gall, Emilie, Devuyst, Olivier, van Eerde, Albertien, Guirchoun, Patrick, Harris, Tess, Hoorn, Ewout J., Knoers, Nine V. A. M., Korst, Uwe, Mekahli, Djalila, Le Meur, Yannick, Nijenhuis, Tom, Ong, Albert C. M., Sayer, John A., Schaefer, Franz, Servais, Aude, Tesar, Vladimir, Torra, Roser, Walsh, Stephen B., Gansevoort, Ron T. |
| بيانات النشر: | OXFORD UNIV PRESS |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Approval of the vasopressin V2 receptor antagonist tolvaptan-based on the landmark TEMPO 3:4 trial-marked a transformation in the management of autosomal dominant polycystic kidney disease (ADPKD). This development has advanced patient care in ADPKD from general measures to prevent progression of chronic kidney disease to targeting disease-specific mechanisms. However, considering the long-term nature of this treatment, as well as potential side effects, evidence-based approaches to initiate treatment only in patients with rapidly progressing disease are crucial. In 2016, the position statement issued by the European Renal Association (ERA) was the first society-based recommendation on the use of tolvaptan and has served as a widely used decision-making tool for nephrologists. Since then, considerable practical experience regarding the use of tolvaptan in ADPKD has accumulated. More importantly, additional data from REPRISE, a second randomized clinical trial (RCT) examining the use of tolvaptan in later-stage disease, have added important evidence to the field, as have post hoc studies of these RCTs. To incorporate this new knowledge, we provide an updated algorithm to guide patient selection for treatment with tolvaptan and add practical advice for its use. |
| مصطلحات الفهرس: | ddc:no, doc-type:article, publishedVersion |
| URL: | 10.1093/ndt/gfab312 |
| الاتاحة: | Open access content. Open access content |
| ملاحظة: | English |
| Other Numbers: | K7U oai:USBKOELN.ub.uni-koeln.de:60669 Mueller, Roman-Ulrich, Messchendorp, A. Lianne, Birn, Henrik, Capasso, Giovambattista ORCID: 0000-0003-3469-8614 <https://orcid.org/0000-0003-3469-8614>, Cornec-Le Gall, Emilie, Devuyst, Olivier ORCID: 0000-0003-3744-4767 <https://orcid.org/0000-0003-3744-4767>, van Eerde, Albertien, Guirchoun, Patrick, Harris, Tess, Hoorn, Ewout J., Knoers, Nine V. A. M., Korst, Uwe, Mekahli, Djalila, Le Meur, Yannick, Nijenhuis, Tom, Ong, Albert C. M., Sayer, John A., Schaefer, Franz, Servais, Aude, Tesar, Vladimir, Torra, Roser, Walsh, Stephen B. and Gansevoort, Ron T. . An update on the use of tolvaptan for autosomal dominant polycystic kidney disease: consensus statement on behalf of the ERA Working Group on Inherited Kidney Disorders, the European Rare Kidney Disease Reference Network and Polycystic Kidney Disease International. Nephrol. Dial. Transplant.. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2385 1364971005 |
| المصدر المساهم: | UNIVERSITATS- UND STADTBIBLIOTHEK KOLN From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1364971005 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |