Electronic Resource
Prediction of good neurological outcome in comatose survivors of cardiac arrest: a systematic review
| العنوان: | Prediction of good neurological outcome in comatose survivors of cardiac arrest: a systematic review |
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| المؤلفون: | Sandroni, Claudio, D'Arrigo, Sonia, Cacciola, Sofia, E Hoedemaekers, Cornelia W, Westhall, Erik, A Kamps, Marlijn J, S Taccone, Fabio, Poole, Daniele, A Meijer, Frederick J, Antonelli, Massimo, G Hirsch, Karen, Soar, Jasmeet, P Nolan, Jerry, Cronberg, Tobias, Claudio Sandroni (ORCID:0000-0002-8878-2611), Sonia D'Arrigo (ORCID:0000-0001-6740-3195), Sofia Cacciola, Cornelia W E Hoedemaekers, Erik Westhall, Marlijn J A Kamps, Fabio S Taccone, Daniele Poole, Frederick J A Meijer, Massimo Antonelli (ORCID:0000-0003-3007-1670), Karen G Hirsch, Jasmeet Soar, Jerry P Nolan, Tobias Cronberg |
| بيانات النشر: | 2022 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Purpose: To assess the ability of clinical examination, blood biomarkers, electrophysiology or neuroimaging assessed within 7 days from return of spontaneous circulation (ROSC) to predict good neurological outcome, defined as no, mild, or moderate disability (CPC 1-2 or mRS 0-3) at discharge from intensive care unit or later, in comatose adult survivors from cardiac arrest (CA). Methods: PubMed, EMBASE, Web of Science and the Cochrane Database of Systematic Reviews were searched. Sensitivity and specificity for good outcome were calculated for each predictor. The risk of bias was assessed using the QUIPS tool. Results: A total of 37 studies were included. Due to heterogeneities in recording times, predictor thresholds, and definition of some predictors, meta-analysis was not performed. A withdrawal or localisation motor response to pain immediately or at 72-96 h after ROSC, normal blood values of neuron-specific enolase (NSE) at 24 h-72 h after ROSC, a short-latency somatosensory evoked potentials (SSEPs) N20 wave amplitude > 4 µV or a continuous background without discharges on electroencephalogram (EEG) within 72 h from ROSC, and absent diffusion restriction in the cortex or deep grey matter on MRI on days 2-7 after ROSC predicted good neurological outcome with more than 80% specificity and a sensitivity above 40% in most studies. Most studies had moderate or high risk of bias. Conclusions: In comatose cardiac arrest survivors, clinical, biomarker, electrophysiology, and imaging studies identified patients destined to a good neurological outcome with high specificity within the first week after cardiac arrest (CA). |
| مصطلحات الفهرس: | Cardiac arrest, Clinical examination, Coma, Computed tomography, Diffusion magnetic resonance imaging, Electroencephalogram, Neuron specific enolase, Prognosi, Somatosensory evoked potentials., Settore MED/41 - ANESTESIOLOGIA, info:eu-repo/semantics/article |
| URL: | issue:48 firstpage:389 lastpage:413 numberofpages:25 issueyear:2022 journal:INTENSIVE CARE MEDICINE |
| الاتاحة: | Open access content. Open access content |
| ملاحظة: | English |
| Other Numbers: | SYC oai:publicatt.unicatt.it:10807/199344 1330709572 |
| المصدر المساهم: | UNIV CATTOLICA DEL SACRO CUORE From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1330709572 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |