Electronic Resource

Non-melanoma skin cancer treated by contact high-dose-rate radiotherapy (brachytherapy): A mono-institutional series and literature review

التفاصيل البيبلوغرافية
العنوان: Non-melanoma skin cancer treated by contact high-dose-rate radiotherapy (brachytherapy): A mono-institutional series and literature review
المؤلفون: Tagliaferri, Luca, Ciardo, Francesco Giuseppe, Fionda, B., Casa, Cristina, Stefani, A. D. I., Lancellotta, V., Placidi, Elisa, Macchia, Gabriella, Capocchiano, Nikola Dino, Morganti, Alessio Giuseppe, Kovacs, Gyorgy, Bussu, Francesco, Peris, Ketty, Valentini, Vincenzo, Tagliaferri L. (ORCID:0000-0003-2308-0982), Ciardo F. G., Casa C., Placidi E., Macchia G., Capocchiano N. D., Morganti A. G., Kovacs G., Bussu F. (ORCID:0000-0001-6261-2772), Peris K. (ORCID:0000-0002-5237-0463), Valentini V. (ORCID:0000-0003-4637-6487)
بيانات النشر: International Institute of Anticancer Research 2021
نوع الوثيقة: Electronic Resource
مستخلص: Background/Aim: Non-melanoma skin cancers (NMSC) are the most common neoplasms worldwide and their incidence has been proven to increase in recent years and their treatment should aim at cancer cure as well as cosmetic and functional results. The aim of the study was to report the results of our mono-institutional series of high-dose-rate radiotherapy (cHDR-RT) in NMSC, based on a homogenous technique and two different treatment schedules. Patients and Methods: All patients affected by NMSC who were consecutively evaluated and treated at our Interventional Oncology Center from October 2018 to August 2020, were included. Patients underwent cHDR-RT using flap applicators and remotely afterloaded Ir-192 sources. Results: Overall, 51 patients were treated for a total of 67 lesions. Local control (LC) and disease-specific survival (DSS) were 94.0% and 100%, respectively. Grade 1, grade 2, grade 3 and grade 4 acute toxicity rates were 24.6%, 3.5%, 3.5%, and 0.0%, respectively. The cosmetic results were graded as excellent/good, fair, and poor in 73.7%, 19.3%, and 7.0%. Conclusion: cHDR-RT of NMSC is an effective alternative to surgery due to excellent outcomes both in terms of local control and aesthetic results especially in the face.
مصطلحات الفهرس: Brachytherapy, Non-melanoma skin cancer, Radiation therapy, Radiotherapy, Esthetics, Humans, Radiotherapy Dosage, Skin Neoplasms, Settore MED/35 - MALATTIE CUTANEE E VENEREE, info:eu-repo/semantics/article
URL: http://hdl.handle.net/10807/197840
info:eu-repo/semantics/altIdentifier/pmid/34182511
info:eu-repo/semantics/altIdentifier/wos/WOS:000664067700002
volume:35
issue:4
firstpage:2313
lastpage:2319
numberofpages:7
issueyear:2021
journal:IN VIVO
الاتاحة: Open access content. Open access content
ملاحظة: English
Other Numbers: SYC oai:publicatt.unicatt.it:10807/197840
10.21873/INVIVO.12505
info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85109087924
1330709245
المصدر المساهم: UNIV CATTOLICA DEL SACRO CUORE
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رقم الانضمام: edsoai.on1330709245
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