Electronic Resource
North African populations carry the signature of admixture with Neandertals
| العنوان: | North African populations carry the signature of admixture with Neandertals |
|---|---|
| المؤلفون: | Sánchez-Quinto, Federico, Botigué, Laura R., Civit, Sergi, Arenas, Conxita, Avila Arcos, Maria del Carmen, Bustamante, Carlos D., Comas, David, Lalueza-Fox, Carles |
| المصدر: | Sánchez-Quinto , F , Botigué , L R , Civit , S , Arenas , C , Avila Arcos , M D C , Bustamante , C D , Comas , D & Lalueza-Fox , C 2012 , ' North African populations carry the signature of admixture with Neandertals ' , PLoS ONE , vol. 7 , no. 10 , e47765 . |
| بيانات النشر: | 2012-10 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | One of the main findings derived from the analysis of the Neandertal genome was the evidence for admixture between Neandertals and non-African modern humans. An alternative scenario is that the ancestral population of non-Africans was closer to Neandertals than to Africans because of ancient population substructure. Thus, the study of North African populations is crucial for testing both hypotheses. We analyzed a total of 780,000 SNPs in 125 individuals representing seven different North African locations and searched for their ancestral/derived state in comparison to different human populations and Neandertals. We found that North African populations have a significant excess of derived alleles shared with Neandertals, when compared to sub-Saharan Africans. This excess is similar to that found in non-African humans, a fact that can be interpreted as a sign of Neandertal admixture. Furthermore, the Neandertal's genetic signal is higher in populations with a local, pre-Neolithic North African ancestry. Therefore, the detected ancient admixture is not due to recent Near Eastern or European migrations. Sub-Saharan populations are the only ones not affected by the admixture event with Neandertals. |
| مصطلحات الفهرس: | Africa South of the Sahara, Africa, Northern, Animals, Asia, Europe, Gene Pool, Genealogy and Heraldry, Genetics, Population, Humans, Neanderthals, Principal Component Analysis, article |
| URL: | |
| الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | application/pdf English |
| Other Numbers: | DAV oai:pure.atira.dk:publications/42552c1b-541f-4aa4-9b32-329246edad56 1322630983 |
| المصدر المساهم: | UNIV OF COPENHAGEN From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1322630983 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |