Electronic Resource
Omics in chronic kidney disease: Focus on prognosis and prediction
| العنوان: | Omics in chronic kidney disease: Focus on prognosis and prediction |
|---|---|
| المؤلفون: | Provenzano, M, Serra, R, Garofalo, C, Michael, A, Crugliano, G, Battaglia, Y, Ielapi, N, Bracale, U, Faga, T, Capitoli, G, Galimberti, S, Andreucci, M, Provenzano M., Serra R., Garofalo C., Michael A., Crugliano G., Battaglia Y., Ielapi N., Bracale U. M., Faga T., Capitoli G., Galimberti S., Andreucci M. |
| بيانات النشر: | MDPI AG country:CH 2022 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Chronic kidney disease (CKD) patients are characterized by a high residual risk for cardiovascular (CV) events and CKD progression. This has prompted the implementation of new prognostic and predictive biomarkers with the aim of mitigating this risk. The ‘omics’ techniques, namely genomics, proteomics, metabolomics, and transcriptomics, are excellent candidates to provide a better understanding of pathophysiologic mechanisms of disease in CKD, to improve risk stratification of patients with respect to future cardiovascular events, and to identify CKD patients who are likely to respond to a treatment. Following such a strategy, a reliable risk of future events for a particular patient may be calculated and consequently the patient would also benefit from the best available treatment based on their risk profile. Moreover, a further step forward can be represented by the aggregation of multiple omics information by combining different techniques and/or different biological samples. This has already been shown to yield additional information by revealing with more accuracy the exact individual pathway of disease. |
| مصطلحات الفهرس: | Albuminuria, Chronic renal failure, Genomic, Metabolomic, Precision medicine, Proteomic, SNP, info:eu-repo/semantics/article |
| URL: | info:eu-repo/semantics/altIdentifier/pmid/35008760 info:eu-repo/semantics/altIdentifier/wos/WOS:000752550800001 volume:23 issue:1 journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
| الاتاحة: | Open access content. Open access content info:eu-repo/semantics/openAccess |
| ملاحظة: | English |
| Other Numbers: | ITBAO oai:boa.unimib.it:10281/348105 10.3390/ijms23010336 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85121779294 1308942921 |
| المصدر المساهم: | BICOCCA OPEN ARCH From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1308942921 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |