Electronic Resource
Cervical re-injection of indocyanine green to improve sentinel lymph node detection in endometrial cancer
| العنوان: | Cervical re-injection of indocyanine green to improve sentinel lymph node detection in endometrial cancer |
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| المؤلفون: | Maramai, M, Achilarre, M, Aloisi, A, Betella, I, Bogliolo, S, Garbi, A, Maruccio, M, Quatrale, C, Aletti, G, Mariani, A, Colombo, N, Maggioni, A, Multinu, F, Zanagnolo, V, Maramai M., Achilarre M. T., Aloisi A., Betella I., Bogliolo S., Garbi A., Maruccio M., Quatrale C., Aletti G. D., Mariani A., Colombo N., Maggioni A., Multinu F., Zanagnolo V. |
| بيانات النشر: | Academic Press Inc. country:US 2021 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Objectives: To evaluate the role of cervical re-injection of indocyanine green (ICG) to increase the detection rate of sentinel lymph node (SLN) in patients with endometrial cancer (EC) who underwent robotic-assisted surgical staging. Methods: We retrospectively identified consecutive EC patients undergoing robotic-assisted staging with SLN biopsy at our Institution between June 2016 and April 2020. Patients were excluded if they had open abdominal surgical approach, neoadjuvant chemotherapy, and advanced stage [International Federation of Gynecology and Obstetrics (FIGO) stage III-IV] at diagnosis. According to our SLN protocol, in case of either unilateral or no SLN detection, we performed an ipsilateral or bilateral cervical re-injection of ICG. Results: In total, 251 patients meeting inclusion criteria were included in the analysis. At first injection, bilateral detection was achieved in 184 (73.3%), unilateral detection in 57 (22.7%), and no detection in 10 (4.0%) patients. Cervical re-injection was performed in 51 of 67 patients with failed bilateral mapping. After cervical re-injection, bilateral detection rate increased to 94.5% (222/235), while unilateral and no detection were 5.1% (12/235) and 0.4% (1/235), respectively. Conclusions: Our results suggest that cervical re-injection of ICG, in case of failed bilateral mapping of SLN, brings about a significant improvement in SLN detection rates, therefore reducing the number of side-specific required lymphadenectomies. |
| مصطلحات الفهرس: | Endometrial cancer, Indocyanine green, Re-injection, Sentinel lymph node algorithm, Surgical staging, info:eu-repo/semantics/article |
| URL: | info:eu-repo/semantics/altIdentifier/pmid/33906784 info:eu-repo/semantics/altIdentifier/wos/WOS:000664094500007 volume:162 issue:1 firstpage:38 lastpage:42 numberofpages:5 journal:GYNECOLOGIC ONCOLOGY |
| الاتاحة: | Open access content. Open access content |
| ملاحظة: | English |
| Other Numbers: | ITBAO oai:boa.unimib.it:10281/327593 10.1016/j.ygyno.2021.04.026 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85106237005 1308940776 |
| المصدر المساهم: | BICOCCA OPEN ARCH From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1308940776 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |