Electronic Resource
Intensive care implications of epidemic thunderstorm asthma.
| العنوان: | Intensive care implications of epidemic thunderstorm asthma. |
|---|---|
| المؤلفون: | McGain F., Vetro J., McCaffrey J., Taori G., Subramaniam A., MacIsaac C., Cross A., Ku D., Bellomo R., Wigmore G., French C., Karalapillai D., Newbigin E., Byrne T., Sarode V., Gelbart B., Pilcher D., Darvall J.N., Durie M., Casamento A., Dyett J., Crosswell A. |
| بيانات النشر: | NLM (Medline) Australia 2019-04-02 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | OBJECTIVE: To investigate the environmental precipitants, treatment and outcome of critically ill patients affected by the largest and most lethal reported epidemic of thunderstorm asthma. DESIGN, SETTING AND PARTICIPANTS: Retrospective multicentre observational study. Meteorological, airborne particulate and pollen data, and a case series of 35 patients admitted to 15 intensive care units (ICUs) due to the thunderstorm asthma event of 21-22 November 2016, in Victoria, Australia, were analysed and compared with 1062 total ICU-admitted Australian patients with asthma in 2016. MAIN OUTCOME MEASURES: Characteristics and outcomes of total ICU versus patients with thunderstorm asthma, the association between airborne particulate counts and storm arrival, and ICU resource utilisation. RESULT(S): All 35 patients had an asthma diagnosis; 13 (37%) had a cardiac or respiratory arrest, five (14%) died. Compared with total Australian ICU-admitted patients with asthma in 2016, patients with thunderstorm asthma had a higher mortality (15% v 1.3%, P < 0.001), were more likely to be male (63% v 34%, P < 0.001), to be mechanically ventilated, and had shorter ICU length of stay in survivors (median, 31.8 hours [interquartile range (IQR), 14.8-43.6 hours] v 40.7 hours [IQR, 22.3-75.1 hours]; P = 0.025). Patients with cardiac arrest were more likely to be born in Asian or subcontinental countries (5/10 [50%] v 4/25 [16%]; relative risk, 3.13; 95% CI, 1.05-9.31). A temporal link was demonstrated between airborne particulate counts and arrival of the storm. The event used 15% of the public ICU beds in the region. CONCLUSION(S): Arrival of a triggering storm is associated with an increase in respirable airborne particles. Affected critically ill patients are young, have a high mortality, a short duration of bronchospasm, and a prior diagnosis of asthma is common. |
| مصطلحات الفهرس: | asthma/ep [Epidemiology], multicenter study, adolescent, adult, aged, air pollution, artificial ventilation, asthma/th [Therapy], child, clinical trial, critical illness/ep [Epidemiology], female, human, intensive care, length of stay, male, middle aged, particulate matter, pollen, procedures, retrospective study, Victoria, weather, young adult, rain, statistics and numerical data, Article |
| URL: | Click here for full text options LibKey Link |
| الاتاحة: | Open access content. Open access content This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine |
| Other Numbers: | AUSHL oai:repository.monashhealth.org:1/37691 Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine. 20 (4) (pp 294-303), 2018. Date of Publication: 01 Dec 2018. 1441-2772 https://repository.monashhealth.org/monashhealthjspui/handle/1/37691 30482137 [http://www.ncbi.nlm.nih.gov/pubmed/?term=30482137] 625211976 (Darvall, Durie, Wigmore, MacIsaac, Bellomo) Department of Intensive Care, Royal Melbourne Hospital, Melbourne, Vic, Australia (Pilcher, Byrne) Department of Intensive Care, Alfred Hospital, Melbourne, Vic, Australia (French, McGain) Department of Intensive Care, Western Health, Melbourne, Vic, Australia (Karalapillai, Casamento) Department of Intensive Care, Austin Hospital, Melbourne, Vic, Australia (Newbigin) School of BioSciences, University of Melbourne, Melbourne, Vic, Australia (Sarode) Department of Intensive Care, Cabrini Hospital, Melbourne, Vic, Australia (Gelbart) Centre for Integrated Critical Care, University of Melbourne, Melbourne, Vic, Australia (Dyett, Vetro) Intensive Care Service, Eastern Health, Box Hill Hospital, Melbourne, Vic, Australia (Crosswell) Department of Intensive Care, St Vincent's Hospital, Melbourne, Vic, Australia (McCaffrey) Department of Intensive Care, University Hospital Geelong, Geelong, Vic, Australia (Taori) Department of Intensive Care, Monash Hospital, Melbourne, Vic, Australia (Subramaniam) Department of Intensive Care, Frankston Hospital, Melbourne, Vic, Australia (Cross) School of Medicine, University of Melbourne, Melbourne, Vic, Australia (Ku) Department of Intensive Care, Dandenong Hospital, Melbourne, Vic, Australia Darvall J.N.; jai.darvall@mh.org.au 1305128848 |
| المصدر المساهم: | MONASH HEALTH LIBRS From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1305128848 |
| قاعدة البيانات: | OAIster |
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