Electronic Resource
Sex differences in outcomes following isolated coronary artery bypass graft surgery in Australian patients: Analysis of the Australasian Society of Cardiac and Thoracic Surgeons cardiac surgery database.
| العنوان: | Sex differences in outcomes following isolated coronary artery bypass graft surgery in Australian patients: Analysis of the Australasian Society of Cardiac and Thoracic Surgeons cardiac surgery database. |
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| المؤلفون: | Smith J.A., Saxena A., Dinh D., Shardey G., Newcomb A.E., Reid C.M. |
| بيانات النشر: | European Association for Cardio-Thoracic Surgery (E-mail: info@eacts.co.uk) Netherlands 2013-07-04 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Objectives: Women undergoing isolated coronary artery bypass graft (CABG) surgery have been previously shown to be at an independently increased risk for post-operative morbidity and mortality. The current study evaluates the impact of sex as an independent risk factor for early and late morbidity and mortality following isolated CABG surgery. Method(s): Data obtained between June 2001 and December 2009 by the Australasian Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database Program was retrospectively analysed. Demographic, operative data and post-operative complications were compared between male and female patients using chi-square and t-tests. Long-term survival analysis was performed using Kaplan-Meier survival curves and the log-rank test. Independent risk factors for short- and long-term mortality were identified using binary logistic and Cox regression, respectively. Result(s): CABG surgery was undertaken in 21 534 patients at 18 Australian institutions; 22.2% were female. Female patients were generally older (mean age, 68 vs. 65 years, P < 0.001) and presented more often with congestive heart failure (P < 0.001), hypertension (P < 0.001), diabetes mellitus (P < 0.001) and cerebrovascular disease (P < 0.001). Women demonstrated a greater 30-day mortality (2.2% vs. 1.5%, P < 0.001) on univariate analysis but not on multivariate analysis (P = 0.638). Similarly, women demonstrated a greater late mortality than men on univariate analysis (P = 0.006) but not on multivariate analysis (P = 0.093). Women had a decreased risk of early complications including new renal failure (P = 0.001) and deep sternal wound infection (P = 0.017) but were more likely to require red blood cell transfusion (P < 0.001). Conclusion(s): Female patients undergoing isolated CABG surgery have a greater 30-day mortality which may be accounted for by a poorer pre-operative risk factor profile. Further investigation is required into the reasons for differential outcome after CABG |
| مصطلحات الفهرس: | male, morbidity, mortality, multivariate analysis, postoperative complication/co [Complication], postoperative hemorrhage/co [Complication], priority journal, proportional hazards model, retrospective study, risk factor, septicemia/co [Complication], surgical infection/co [Complication], surgical mortality, survival rate, treatment outcome, wound infection/co [Complication], sex difference, aged, article, Australia, cardiac patient, cerebrovascular disease/su [Surgery], congestive heart failure/su [Surgery], controlled study, coronary artery bypass graft, diabetes mellitus/su [Surgery], female, heart surgery, human, hypertension/su [Surgery], Kaplan Meier method, kidney failure/co [Complication], log rank test, long term survival, major clinical study, Article |
| URL: | European Journal of Cardio-thoracic Surgery LibKey Link |
| الاتاحة: | Open access content. Open access content Copyright 2017 Elsevier B.V., All rights reserved. |
| Other Numbers: | AUSHL oai:repository.monashhealth.org:1/28119 European Journal of Cardio-thoracic Surgery. 41 (4) (pp 755-762), 2012. Date of Publication: 2012. 1010-7940 https://repository.monashhealth.org/monashhealthjspui/handle/1/28119 Cardiothoracic Surgery 22423056 [http://www.ncbi.nlm.nih.gov/pubmed/?term=22423056] 366299906 (Saxena, Newcomb) Department of Cardiothoracic Surgery, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia (Dinh, Reid) Department of Epidemiology and Preventative Medicine, Monash University, Prahran, VIC, Australia (Smith) Department of Surgery (MMC), Monash University, Clayton, VIC, Australia (Smith) Department of Cardiothoracic Surgery, Monash Medical Centre, Clayton, VIC, Australia (Shardey) Cabrini Medical Centre, Malvern, VIC, Australia (Newcomb) Department of Surgery, St Vincent's Hospital Melbourne, University of Melbourne, Fitzroy, VIC, Australia Newcomb A.E.; andrew.newcomb@svhm.org.au 1305120175 |
| المصدر المساهم: | MONASH HEALTH LIBRS From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1305120175 |
| قاعدة البيانات: | OAIster |
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