Electronic Resource
Treatment of preeclampsia with hydroxychloroquine: a review.
| العنوان: | Treatment of preeclampsia with hydroxychloroquine: a review. |
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| المؤلفون: | Abd Rahman R., DeKoninck P., Murthi P., Wallace E.M. |
| بيانات النشر: | Taylor and Francis Ltd (E-mail: healthcare.enquiries@informa.com) United Kingdom 2018-02-05 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | In this review, we discuss the potential use of antimalarial drugs as an adjuvant therapy for preeclampsia, focusing on the mechanisms of action of this class of drugs in the context of preeclampsia. In particular, hydroxychloroquine has been shown to have various beneficial effects on patients with systemic lupus erythematosus. There are several pathways targeted by the antimalarial drugs that are similar to the pathophysiology of preeclampsia and hence offering opportunities to develop novel therapies to treat the disease. Given the safety profile of hydroxychloroquine in pregnancy, there is merit in exploring the efficacy of this drug as an adjuvant therapy in women with early onset preeclampsia.Copyright © 2017 Informa UK Limited, trading as Taylor & Francis Group. |
| مصطلحات الفهرس: | preeclampsia/dt [Drug Therapy], priority journal, pruritus/si [Side Effect], review, hydroxychloroquine/ae [Adverse Drug Reaction], hydroxychloroquine/dt [Drug Therapy], hydroxychloroquine/pd [Pharmacology], reduced nicotinamide adenine dinucleotide phosphate oxidase/ec [Endogenous Compound], toll like receptor 3/ec [Endogenous Compound], toll like receptor 7/ec [Endogenous Compound], toll like receptor 9/ec [Endogenous Compound], vascular protective effect, drug safety, adjuvant therapy, antiinflammatory activity, antioxidant activity, cell protection, drug effect, drug efficacy, drug mechanism, drug targeting, enzyme activity, gastrointestinal symptom/si [Side Effect], headache/si [Side Effect], human, nonhuman, oxidative stress, pathophysiology, Review |
| URL: | Journal of Maternal-Fetal and Neonatal Medicine Click here for full text options LibKey Link |
| الاتاحة: | Open access content. Open access content Copyright 2018 Elsevier B.V., All rights reserved. |
| Other Numbers: | AUSHL oai:repository.monashhealth.org:1/37605 Journal of Maternal-Fetal and Neonatal Medicine. 31 (4) (pp 525-529), 2018. Date of Publication: 16 Feb 2018. 1476-7058 https://repository.monashhealth.org/monashhealthjspui/handle/1/37605 Obstetrics and Gynaecology (Monash Women's) Murthi, Padma; ORCID: http://orcid.org/0000-0003-2535-5134 Wallace, Euan M.; ORCID: http://orcid.org/0000-0002-4506-5233 28142291 [http://www.ncbi.nlm.nih.gov/pubmed/?term=28142291] 620338254 (Abd Rahman) Department of Obstetrics and Gynecology, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia (DeKoninck, Murthi, Wallace) Department of Medicine, School of Clinical Sciences, Monash University, Monash Medical Centre, Clayton, VIC, Australia (Abd Rahman, Wallace) The Ritchie Centre, Hudson Institute of Medical Research, Clayton, VIC, Australia Wallace E.M.; euan.wallace@monash.edu 1305107802 |
| المصدر المساهم: | MONASH HEALTH LIBRS From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1305107802 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |