Electronic Resource
A phase 1 study of a novel bidirectional femoral arterial cannula for the prevention of leg ischemia during cardiac surgical procedures.
| العنوان: | A phase 1 study of a novel bidirectional femoral arterial cannula for the prevention of leg ischemia during cardiac surgical procedures. |
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| المؤلفون: | Moshinsky R.A., Marasco S.F., Tutungi E., Pellegrino V.A., Vallance S.A. |
| بيانات النشر: | Lippincott Williams and Wilkins Netherlands 2018-03-22 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Objective: Leg ischemia is a serious complication of femoral artery cannulation. A novel bidirectional femoral arterial cannula (Sorin Group USA, a wholly owned subsidiary of LivaNova PLC, Arvada, CO USA) that provides both antegrade and retrograde flow was evaluated in this study. The safety and efficacy of this device were evaluated in patients undergoing cardiac surgical procedures requiring peripheral cannulation for cardiopulmonary bypass (CPB). Method(s): Written informed consent was obtained in the ambulatory setting. After induction of anesthesia, all cannulas were inserted directly into the femoral artery via a surgical cutdown and awire-through-needle technique. Flow in the superficial femoral artery (SFA) was assessed using Doppler ultrasound after commencement of CPB. Lower limb perfusion was assessed using near-infrared reflectance spectroscopy as a measure of regional oxygen saturation. A baseline measure was obtained prior to cannulation, at the commencement of CPB, and then every 15 minutes. Result(s): Six patients (median age 63.5 years, range 35-77) underwent femoral arterial cannulation using the novel bidirectional femoral arterial cannula at the Alfred Hospital, Melbourne, Australia, between August and December 2016. Indications included minimally invasive thoracotomy because of coagulopathy and poor pulmonary complianceThis patient and the smallest patient (surgical weight, 420 g) (3.2%) died of bronchial bleeding. There was 1 hospital death of renal failure. Sixty patients (95.2%) were discharged home without any complications. The mean follow-up period was 70 months. Follow-up examinations have demonstrated no residual shunts and no late deaths. The multiple regression analyses (Cox regression hazard model) indicated that the body weight at surgery is the only potential risk factor for death (hazard ratio, 0.976, 95% CI, 0.956-0.997, P = 0.025). Conclusion(s): The VATS technique is safe and less invasive and provides excellent surgical result |
| مصطلحات الفهرس: | hazard ratio, heart surgery, human, informed consent, kidney failure, leg ischemia, limb perfusion, major clinical study, male, middle aged, multiple regression, near infrared reflectance spectroscopy, newborn, oxygen saturation, phase 1 clinical trial, prevention, proportional hazards model, risk factor, superficial femoral artery, surgery, thoracotomy, endogenous compound, phosphatidylinositol 4,5 bisphosphate phosphodiesterase, conference abstract, adult, anesthesia induction, Australia, bleeding, blood clotting disorder, bronchus, cannula, cannulation, cardiopulmonary bypass, clinical evaluation, complication, controlled study, death, Doppler flowmetry, extremely low birth weight, female, follow up, Conference Abstract |
| URL: | LibKey Link |
| الاتاحة: | Open access content. Open access content Copyright 2018 Elsevier B.V., All rights reserved. |
| Other Numbers: | AUSHL oai:repository.monashhealth.org:1/38919 Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. Conference: 20th Annual Meeting of the International Society for Minimally Invasive Cardiothoracic Surgery, ISMICS 2017. Rome Italy. 12 (Supplement 4) (pp S119-S120), 2017. Date of Publication: December 2017. 1559-0879 https://repository.monashhealth.org/monashhealthjspui/handle/1/38919 621289164 (Marasco, Pellegrino, Vallance) Alfred Hospital, Melbourne, Australia (Tutungi) Cabrini Hospital, Melbourne, Australia (Moshinsky) Monash Medical Centre, Melbourne, Australia (Marasco, Pellegrino, Vallance) Alfred Hospital, Melbourne, Australia (Tutungi) Cabrini Hospital, Melbourne, Australia (Moshinsky) Monash Medical Centre, Melbourne, Australia 1305107496 |
| المصدر المساهم: | MONASH HEALTH LIBRS From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1305107496 |
| قاعدة البيانات: | OAIster |
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