Electronic Resource
Analysis of Fine Motor Skills in Essential Tremor: Combining Neuroimaging and Handwriting Biomarkers for Early Management
| العنوان: | Analysis of Fine Motor Skills in Essential Tremor: Combining Neuroimaging and Handwriting Biomarkers for Early Management |
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| المؤلفون: | Universidad del País Vasco, University of Cambridge, Eusko Jaurlaritza, Sociedad Española de Ingeniería Biomédica, Ministerio de Ciencia e Innovación (España), European Commission, Fundación DomusVi, Diputación Foral de Gipuzkoa, European Cooperation in Science and Technology, Lopez-de-Ipina, K., Solé-Casals, J., Sánchez-Méndez, J.I., Romero-Garcia, R., Fernandez, Elsa, Requejo, Catalina, Poologaindran, A., Faúndez-Zanuy, M., Martí-Massó, J. F., Bergareche, A., Suckling, J. |
| بيانات النشر: | Frontiers Media 2021 |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Essential tremor (ET) is a highly prevalent neurological disorder characterized by action-induced tremors involving the hand, voice, head, and/or face. Importantly, hand tremor is present in nearly all forms of ET, resulting in impaired fine motor skills and diminished quality of life. To advance early diagnostic approaches for ET, automated handwriting tasks and magnetic resonance imaging (MRI) offer an opportunity to develop early essential clinical biomarkers. In this study, we present a novel approach for the early clinical diagnosis and monitoring of ET based on integrating handwriting and neuroimaging analysis. We demonstrate how the analysis of fine motor skills, as measured by an automated Archimedes’ spiral task, is correlated with neuroimaging biomarkers for ET. Together, we present a novel modeling approach that can serve as a complementary and promising support tool for the clinical diagnosis of ET and a large range of tremors. |
| مصطلحات الفهرس: | Essential tremor, fine motor skills, Neuroimaging, handwriting, Early management, artículo |
| URL: | Publisher's version Sí info:eu-repo/grantAgreement/MICINN/Ministerio de Ciencia e Innovación SAF201677758R |
| الاتاحة: | Open access content. Open access content https://creativecommons.org/licenses/by/4.0 openAccess |
| Other Numbers: | CTK oai:digital.csic.es:10261/257688 Frontiers in Human Neuroscience 15 (2021) 10.3389/fnhum.2021.648573 34168544 1293837879 |
| المصدر المساهم: | CSIC From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1293837879 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |