Electronic Resource
The seroprevalence of SARS-CoV-2 antibodies among health care workers before the era of vaccination: a systematic review and meta-analysis
| العنوان: | The seroprevalence of SARS-CoV-2 antibodies among health care workers before the era of vaccination: a systematic review and meta-analysis |
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| المؤلفون: | Department of Industrial Engineering, Kayı, İlker (ORCID 0000-0002-4115-6613 & YÖK ID 168599); Madran, Bahar; Keske, Şiran (ORCID 0000-0003-3823-4454 & YÖK ID 125555); Karanfil, Özge (ORCID 0000-0002-2319-0818 & YÖK ID 294019); Gönen, Mehmet (ORCID 0000-0002-2483-075X & YÖK ID 237468); Ergönül, Mehmet Önder (ORCID 0000-0003-1935-9235 & YÖK ID 110398), Arribas, Jose Ramon; Pshenichnaya, Natalia; Petrosillo, Nicola |
| المصدر: | Clinical Microbiology and Infection |
| بيانات النشر: | Elsevier 2021 |
| نوع الوثيقة: | Electronic Resource |
| Supplemental Data: | School of Medicine; Graduate School of Health Sciences; College of Engineering |
| مستخلص: | Background: the prevalence of SARS-CoV-2 infection among health care workers (HCWs) provides information about the spread of COVID-19 within health care facilities, and the risk groups. Objectives: We aimed to describe the rate of SARS-CoV-2 seroprevalence and its determinants among HCWs. Data sources: we used Web of Science, PubMed, Scopus, MEDLINE, EBSCOhost and Cochrane Library. Study eligibility criteria: we included the reports of SARS-CoV-2 seroprevalence with a sample size of minimum 1000 HCWs. Methods: the study was registered at the International Prospective Register of Systematic Reviews (PROSPERO, no. CRD42021230456). We used PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. The keywords were “COVID-19”, “SARS-CoV-2”, “Coronavirus”, “seroprevalence”, “health care workers” and “risk factors”. Results: in total 4329 reports were retrieved, duplications were removed; after filtering according to the title and abstract, 25 studies were selected. Risk of bias was assessed in 25 studies; it was low in 13 studies, medium in four studies, and high in eight studies. In meta-analysis using the random effect model, the weighted average of seroprevalence was calculated as 8% (95% CI 6–10%). The pooled seroprevalence rates of the selected variables that have a rate above the average were male HCWs with 9% (95% CI 7–11%); HCWs from ethnic minorities with 13% (95% CI 9–17%); high exposure 9% (95% CI 6–13%); exposure to the virus outside the health care setting 22% (95% CI 14–32%). Conclusions: our analysis indicates a SARS-CoV-2 seroprevalence rate of 8% among studies that included >1000 HCWs for the year 2020, before vaccinations started. The most common risk factors associated with higher seroprevalence rate were ethnicity, male gender and having a higher number of household contacts. Working as a frontline HCW was inconsistent in its association with higher seroprevalence. |
| مصطلحات الفهرس: | Infectious diseases; Microbiology, Before vaccination; Covid-19; Healthcare workers; Risk factors; Seroprevalence, Review, text/academic publication |
| URL: | Koç University Institutional Repository References NA |
| الاتاحة: | Open access content. Open access content |
| ملاحظة: | pdf NA English |
| Other Numbers: | T9K oai:libdigitalcollections.ku.edu.tr:IR/9680 https://dx.doi.org/10.1016/j.cmi.2021.05.036 IR03024.pdf 1292471785 |
| المصدر المساهم: | KOC UNIV LIBR From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1292471785 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |