Academic Journal
Evolutionary interplay between sister cytochrome P450 genes shapes plasticity in plant metabolism
| العنوان: | Evolutionary interplay between sister cytochrome P450 genes shapes plasticity in plant metabolism |
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| المؤلفون: | Liu, Zhenhua, Tavares, Raquel, Forsythe, Evan S., André, François, Lugan, Raphaël, Jonasson, Gabriella, Boutet-Mercey, Stéphanie, Tohge, Takayuki, Beilstein, Mark A., Werck-Reichhart, Danièle, Renault, Hugues |
| Thesis Advisors: | Univ Arizona, Sch Plant Sci |
| بيانات النشر: | NATURE PUBLISHING GROUP, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | University of Arizona |
| Original Material: | Evolutionary interplay between sister cytochrome P450 genes shapes plasticity in plant metabolism 2016, 7:13026 Nature Communications Nature Communications |
| الوصف: | Expansion of the cytochrome P450 gene family is often proposed to have a critical role in the evolution of metabolic complexity, in particular in microorganisms, insects and plants. However, the molecular mechanisms underlying the evolution of this complexity are poorly understood. Here we describe the evolutionary history of a plant P450 retrogene, which emerged and underwent fixation in the common ancestor of Brassicales, before undergoing tandem duplication in the ancestor of Brassicaceae. Duplication leads first to gain of dual functions in one of the copies. Both sister genes are retained through subsequent speciation but eventually return to a single copy in two of three diverging lineages. In the lineage in which both copies are maintained, the ancestral functions are split between paralogs and a novel function arises in the copy under relaxed selection. Our work illustrates how retrotransposition and gene duplication can favour the emergence of novel metabolic functions. |
| Original Identifier: | oai:arizona.openrepository.com:10150/621949 |
| نوع الوثيقة: | Article |
| اللغة: | English |
| تدمد: | 2041-1723 |
| DOI: | 10.1038/ncomms13026 |
| الاتاحة: | http://hdl.handle.net/10150/621949 http://arizona.openrepository.com/arizona/handle/10150/621949 |
| Rights: | © The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License. |
| رقم الانضمام: | edsndl.arizona.edu.oai.arizona.openrepository.com.10150.621949 |
| قاعدة البيانات: | Networked Digital Library of Theses & Dissertations |
Full Text Finder | تدمد: | 20411723 |
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| DOI: | 10.1038/ncomms13026 |