Academic Journal
Optimization of spray-drying conditions and quality assessment of dry extract from Perilla frutescens (L.) Britton leaves
| العنوان: | Optimization of spray-drying conditions and quality assessment of dry extract from Perilla frutescens (L.) Britton leaves |
|---|---|
| المؤلفون: | Nguyen Thi Linh Tuyen, Nguyen Thi Thuy Linh, Pham Thi To Lien, Do Quang Duong |
| المصدر: | Journal of Pharmacy & Pharmacognosy Research, Vol 12, Iss 6, Pp 1056-1066 (2024) |
| بيانات النشر: | GarVal Editorial Ltda., 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Therapeutics. Pharmacology LCC:Pharmacy and materia medica |
| مصطلحات موضوعية: | bcpharsoft software, dry extract, perilla frutescens, spray-drying, herbal, traditional medicine, medicinal plant, natural product, pharmacognosy, pharmacy, pharmaceutical science, pharmaceutical technology, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441 |
| الوصف: | Context: Perilla frutescens and its dried extract have been employed in food and pharmaceutical manufacturing due to the plant's biological activities, which include antibacterial, anti-allergic, anticancer, antiviral, antioxidant, and antidepressant properties. Despite numerous studies on preparing dry extracts from various medicinal herbs, no research has been conducted to optimize spray-drying conditions specifically for P. frutescens. Aims: To optimize the spray-drying parameters using BCPharSoft software and evaluate the quality of P. frutescens dry extract. Methods: D-optimal design based on four independent variables carrier type (Glucidex, Glucidex: Arabic gum 9:1, Glucidex: Arabic gum 8:2), carrier mass (10, 15, and 20 g), inlet air temperature (160, and 180℃) and flow rate (12, and 14 rpm/min) was applied to investigate the cause-effect relations and optimized preparation process. The drying performance, moisture content, total phenol, and total flavonoid content were investigated as four dependent variables. Results: All independent variables had significant effects on the dependent variables. The optimal parameters of the preparation process included using carrier Glucidex: Arabic gum at a ratio of 9:1, carrier mass of 19 g, inlet air temperature of 161°C, and flow rate of 12 rpm/min. The drying performance, moisture content, total phenol, and flavonoid content of the optimized P. frutescens dry extract were found to be 10.42%, 4.80%, and 90.57 mg GA/g, and 53.55 mg QE/g, respectively. Conclusions: Dried P. frutescens extract has been efficiently produced using the spray-drying technique, establishing a foundation for future manufacturing of pharmaceuticals and functional foods derived from P. frutescens. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Spanish; Castilian |
| تدمد: | 0719-4250 |
| Relation: | https://jppres.com/jppres/pdf/vol12/jppres24.2009_12.6.1056.pdf; https://doaj.org/toc/0719-4250 |
| DOI: | 10.56499/jppres24.2009_12.6.1056 |
| URL الوصول: | https://doaj.org/article/efeea9db1c574bdea993ad63240a928b |
| رقم الانضمام: | edsdoj.feea9db1c574bdea993ad63240a928b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 07194250 |
|---|---|
| DOI: | 10.56499/jppres24.2009_12.6.1056 |