Academic Journal

Interaction between Highly Diluted Samples, Protein Solutions and Water in a Controlled Magnetic Field

التفاصيل البيبلوغرافية
العنوان: Interaction between Highly Diluted Samples, Protein Solutions and Water in a Controlled Magnetic Field
المؤلفون: Vadim V. Novikov, Elena V. Yablokova
المصدر: Applied Sciences, Vol 12, Iss 10, p 5185 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Technology
LCC:Engineering (General). Civil engineering (General)
LCC:Biology (General)
LCC:Physics
LCC:Chemistry
مصطلحات موضوعية: water, weak magnetic field, distant effect, high dilutions, neutrophils, chemiluminescence, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999
الوصف: We have previously shown that water incubated in a weak combined magnetic field (CMF) increased the production of reactive oxygen species (ROS) by neutrophils. Adding high dilutions (HD) of water into the same system resulted in a similar effect. HD of antibodies to interferon-gamma (HD Abs to IFNγ) were shown to emit electromagnetic radiation and affect hydrogen bond energies. Here, we aimed to evaluate the effect of HD of substances (donor) on the properties of aqueous solutions (acceptor). The donor and acceptor were incubated for 1 h in a controlled magnetic field so that the walls of the two cuvettes were in close contact. As a control, the acceptor was incubated under the same conditions but without the donor. An aliquot of the acceptor solution was then added to mouse neutrophils, and ROS levels were measured using luminol-dependent chemiluminescence assay. Joint incubation led to a 185–356% increase (p < 0.05) in ROS production, depending on the type of acceptor sample. The magnitude of the effect depended on the parameters of the magnetic field. In a CMF, the effect was strongest, completely disappearing in a magnetic vacuum or with shielding. These findings are important for understanding the physical mechanism of action of HD preparations, which opens up opportunities for expanding their practical applications.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2076-3417
Relation: https://www.mdpi.com/2076-3417/12/10/5185; https://doaj.org/toc/2076-3417
DOI: 10.3390/app12105185
URL الوصول: https://doaj.org/article/fda0ed4dfdfb4af4b5f91a862694126d
رقم الانضمام: edsdoj.fda0ed4dfdfb4af4b5f91a862694126d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20763417
DOI:10.3390/app12105185