Academic Journal
Lessons Learned about Pneumonic Plague Diagnosis from 2 Outbreaks, Democratic Republic of the Congo
العنوان: | Lessons Learned about Pneumonic Plague Diagnosis from 2 Outbreaks, Democratic Republic of the Congo |
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المؤلفون: | Eric Bertherat, Philippe Thullier, Jean Christophe Shako, Kathleen England, Mamadou-Lamine Koné, Lorraine Arntzen, Herbert Tomaso, Louis Koyange, Pierre Formenty, Florent Ekwanzala, Rosa Crestani, Isa Ciglenecki, Lila Rahalison |
المصدر: | Emerging Infectious Diseases, Vol 17, Iss 5, Pp 778-784 (2011) |
بيانات النشر: | Centers for Disease Control and Prevention, 2011. |
سنة النشر: | 2011 |
المجموعة: | LCC:Medicine LCC:Infectious and parasitic diseases |
مصطلحات موضوعية: | bacteria, Yersinia pestis, plague, pneumonic plague, outbreak response, rapid diagnosis, Medicine, Infectious and parasitic diseases, RC109-216 |
الوصف: | Pneumonic plague is a highly transmissible infectious disease for which fatality rates can be high if untreated; it is considered extremely lethal. Without prompt diagnosis and treatment, disease management can be problematic. In the Democratic Republic of the Congo, 2 outbreaks of pneumonic plague occurred during 2005 and 2006. In 2005, because of limitations in laboratory capabilities, etiology was confirmed only through retrospective serologic studies. This prompted modifications in diagnostic strategies, resulting in isolation of Yersinia pestis during the second outbreak. Results from these outbreaks demonstrate the utility of a rapid diagnostic test detecting F1 antigen for initial diagnosis and public health management, as well as the need for specialized sampling kits and trained personnel for quality specimen collection and appropriate specimen handling and preservation for plague confirmation and Y. pestis isolation. Efficient frontline management and a streamlined diagnostic strategy are essential for confirming plague, especially in remote areas. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1080-6040 1080-6059 |
Relation: | https://wwwnc.cdc.gov/eid/article/17/5/10-0029_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059 |
DOI: | 10.3201/eid1705.100029 |
URL الوصول: | https://doaj.org/article/fc842736c3f848058fbe292822c35c0a |
رقم الانضمام: | edsdoj.fc842736c3f848058fbe292822c35c0a |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 10806040 10806059 |
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DOI: | 10.3201/eid1705.100029 |