Academic Journal
Investigating the impact of the sperm DNA fragmentation index of male partners from infertile couples on in vitro fertilization-embryo transfer outcomes
| العنوان: | Investigating the impact of the sperm DNA fragmentation index of male partners from infertile couples on in vitro fertilization-embryo transfer outcomes |
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| المؤلفون: | Qinglin Qi, Yingchun Su, Jie Peng |
| المصدر: | Journal of Men's Health, Vol 20, Iss 5, Pp 149-154 (2024) |
| بيانات النشر: | MRE Press, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | sperm dna fragmentation index, semen parameters, in vitro fertilization-embryo transfer, Medicine (General), R5-920 |
| الوصف: | This study was aimed to elucidate the relationship between sperm DNA fragmentation index (DFI) and semen parameters, and to investigate the impact of these parameters on in vitro fertilization-embryo transfer (IVF-ET) outcomes. The study was conducted on 159 couples undergoing IVF-ET treatment at the Department of Reproductive Health from January 2019 to October 2023. The case group was comprised of 79 patients with sperm DFI of ≥15%, and the control group had 80 patients with 0.05). However, marked differences were found in the rates of sperm progressive motility, total sperm motility, normal morphology, high-quality embryos, and transferable embryos (p < 0.05). The correlation analysis between sperm DFI and semen parameters exhibited positive correlation between sperm DFI and total sperm count (p < 0.05). The negative correlations were found between the sperm DFI and sperm progressive motility, total sperm motility, or normal morphology (p < 0.01). The findings demonstrated that incorporating sperm DFI as a standard component of semen analysis was advisable, and the sperm DFI as reference tool assisted in predicting the early embryonic development in IVF-ET patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1875-6867 1875-6859 |
| Relation: | https://oss.jomh.org/files/article/20240530-288/pdf/JOMH2023102801.pdf; https://doaj.org/toc/1875-6867; https://doaj.org/toc/1875-6859 |
| DOI: | 10.22514/jomh.2024.048 |
| URL الوصول: | https://doaj.org/article/fbdf9985d6d041068e258f4539d7875f |
| رقم الانضمام: | edsdoj.fbdf9985d6d041068e258f4539d7875f |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 18756867 18756859 |
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| DOI: | 10.22514/jomh.2024.048 |