Academic Journal
Gamma glutamyltransferase, inflammation and cardiovascular risk factors in isolated coronary artery ectasia
| العنوان: | Gamma glutamyltransferase, inflammation and cardiovascular risk factors in isolated coronary artery ectasia |
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| المؤلفون: | Abdullah Dogan, Akif Arslan, Habil Yucel, Fatih Aksoy, Atilla Icli, Mehmet Ozaydin, Ercan Varol, Dogan Erdogan |
| المصدر: | Revista Portuguesa de Cardiologia, Vol 35, Iss 1, Pp 33-39 (2016) |
| بيانات النشر: | Elsevier, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Introduction and Objective: There are conflicting data on the prevalence of cardiovascular risk factors in coronary artery ectasia (CAE). It is unclear whether CAE is associated with high-sensitivity C-reactive protein (hs-CRP) and gamma glutamyltransferase (GGT). We therefore investigated major cardiovascular risk factors, serum GGT and hs-CRP levels in a large population of patients with CAE. Methods: A total of 167 patients with isolated CAE and 150 controls with normal coronary arteries were selected from 10 505 patients undergoing coronary angiography. Serum GGT and hs-CRP levels were evaluated in addition to cardiovascular risk factors including family history, obesity, smoking, diabetes, hypertension and hyperlipidemia. Results: Hypertension and obesity were slightly more prevalent in CAE patients than in controls, whereas diabetes was slightly less frequent in CAE patients. Other risk factors were similar. Serum GGT (22 [17–42] vs. 16 [13–21] U/l, p=0.001) and hs-CRP (2.9 [1.9–3.6] vs. 1.4 [1.1–1.8] mg/l, p=0.001) levels were higher in CAE patients than in controls. The presence of CAE was independently associated with diabetes (OR: 0.44, 95% CI: 0.20–0.95, p=0.04), obesity (OR: 2.84, 95% CI: 1.07–7.56, p=0.04), GGT (OR: 1.08, 95% CI: 1.03–1.12, p=0.001) and hs-CRP levels (OR: 3.1, 95% CI: 2.1–4.6, p=0.001). In addition, GGT and hs-CRP levels were higher in diffuse and multivessel ectasia subgroups than focal and single-vessel ectasia subgroups (each p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 0870-2551 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S0870255115003170; https://doaj.org/toc/0870-2551 |
| DOI: | 10.1016/j.repc.2015.05.009 |
| URL الوصول: | https://doaj.org/article/fac8b47bd7c1494eb3de9b492bcb5c92 |
| رقم الانضمام: | edsdoj.fac8b47bd7c1494eb3de9b492bcb5c92 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 08702551 |
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| DOI: | 10.1016/j.repc.2015.05.009 |