Academic Journal
Pseudoternary Phase Diagram and Antibacterial Activity of Microemulsion-Based Citronella Oil
| العنوان: | Pseudoternary Phase Diagram and Antibacterial Activity of Microemulsion-Based Citronella Oil |
|---|---|
| المؤلفون: | Chintya Gunarto, Alchris Woo Go, Artik Elisa Angkawijaya, Jenni Lie, Felycia Edi Soetaredjo, Suryadi Ismadji, Nathania Puspitasari, Jindrayani Nyoo Putro, Chandra Risdian |
| المصدر: | Indonesian Journal of Chemistry, Vol 24, Iss 3, Pp 900-907 (2024) |
| بيانات النشر: | Department of Chemistry, Universitas Gadjah Mada, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | microemulsion, citronella oil, tween 80, pseudoternary phase diagram, antibacterial, Chemistry, QD1-999 |
| الوصف: | Citronella oil (CTO) is extracted from citronella leaves by maceration or steam distillation process, which has antibacterial and insect-repellent activities. However, the use of CTO is limited and requires modification in other formulations, such as microemulsion (ME), to increase its bioactivities. ME consists of oil, water, surfactant and/or cosurfactant and is commonly applied in food and beverages, cosmetics, and carrier for drug delivery applications. CTO was used as the oil phase for ME with nonionic surfactant and ethanol as a cosurfactant for lowering interfacial tension between oil and water phase. Subsequent observations regarding stability and antibacterial tests were carried out on ME formulations with surfactant/cosurfactant mixture of 2 due to its largest ME area. A hydrodynamic diameter analysis was also carried out to see the stability of the ME within a period of 50 d. ME with 10% CTO, 30% surfactant mixture, and 60% water showed the best formulation observed from the consistent hydrodynamic diameter measurement. In addition, ME with different formulations could inhibit the growth of Escherichia coli and Staphylococcus aureus by more than 90%. From this research, CTO-based ME potentially improve and develop drug carrier applications, especially via topical route. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1411-9420 2460-1578 |
| Relation: | https://jurnal.ugm.ac.id/ijc/article/view/93250; https://doaj.org/toc/1411-9420; https://doaj.org/toc/2460-1578 |
| DOI: | 10.22146/ijc.93250 |
| URL الوصول: | https://doaj.org/article/efa37759b8df4444bca43162d4a5546d |
| رقم الانضمام: | edsdoj.fa37759b8df4444bca43162d4a5546d |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 14119420 24601578 |
|---|---|
| DOI: | 10.22146/ijc.93250 |