Academic Journal
Shear-wave elastography for the assessment of testicular involvement of hematologic malignancies in children and young adults: a feasibility study
| العنوان: | Shear-wave elastography for the assessment of testicular involvement of hematologic malignancies in children and young adults: a feasibility study |
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| المؤلفون: | Seok Young Koh, Seunghyun Lee, Seul Bi Lee, Yeon Jin Cho, Young Hun Choi, Jung-Eun Cheon, Woo Sun Kim |
| المصدر: | Ultrasonography, Vol 41, Iss 2, Pp 325-334 (2022) |
| بيانات النشر: | Korean Society of Ultrasound in Medicine, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medical technology |
| مصطلحات موضوعية: | testis, leukemia, ultrasonography, elastography, child, Medical technology, R855-855.5 |
| الوصف: | Purpose This study aimed to assess the feasibility of shear-wave elastography (SWE) for assessing the testicular involvement of hematologic malignancies in children and young adults. Methods Eight patients (mean age, 11.0 years; range, 0.8 to 20 years) with biopsy-confirmed testicular involvement of hematologic malignancy between January 2018 and December 2020 were retrospectively evaluated. Multiparametric ultrasound examinations, including grayscale, color Doppler ultrasonography (CDUS), and SWE, were performed. Stiffness was measured in the involved testicular area and contralateral normal parenchyma. If there was bilateral testicular involvement, the stiffness of the involved area and the adjacent normal echoic parenchyma was measured on one testis. The Mann-Whitney U test was used to compare stiffness values. Results On grayscale, the testicular lesions were noted as a solitary mass in one patient, multiple lesions in four patients, and diffuse involvement in three patients. On CDUS and SWE, all patients demonstrated increased vascularity, and the stiffness of the involved area was higher than the values of normal parenchyma (the involved area vs. normal parenchyma, 11.6 kPa [3.9-20.2 kPa] vs. 2.9 kPa [1.1-3.7 kPa], P=0.003). The ratio of stiffness between the involved area and normal parenchyma was 3.4, ranging from 1.9 to 5.1. One patient showed decreased stiffness on follow-up SWE after treatment (affected testis vs. normal testis: initial, 13.8 vs. 3.2 kPa; 1 year later, 2.2 vs. 2.4 kPa). Conclusion Increased testicular stiffness on SWE in children and young adults with hematologic malignancies suggests the possibility of testicular involvement. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2288-5919 2288-5943 |
| Relation: | http://www.e-ultrasonography.org/upload/usg-21072.pdf; https://doaj.org/toc/2288-5919; https://doaj.org/toc/2288-5943 |
| DOI: | 10.14366/usg.21072 |
| URL الوصول: | https://doaj.org/article/f8f6a125d2ee4b0bad9af748540ef852 |
| رقم الانضمام: | edsdoj.f8f6a125d2ee4b0bad9af748540ef852 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22885919 22885943 |
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| DOI: | 10.14366/usg.21072 |